ArticlePLOS global public health2025
Determinants of COVID-19 vaccine hesitancy among healthcare personnel in a secondary-level health facility in Ghana.
Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Perspectives on postpartum continuity of antiretroviral therapy care at Volta Regional Hospital, Ghana.BMC pregnancy and childbirth · 2026Article
- Predictors of COVID-19 vaccination intention among students in Ghana: An application of the Health Belief Model and Theory of Planned Behaviour.PLOS global public health · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vaccine hesitancy has been a long-standing concern globally and emerged during the COVID-19 pandemic among healthcare personnel. This study assessed the prevalence and determinants of vaccine hesitancy among healthcare personnel at the Volta Regional Hospital in Ghana. A cross-sectional study was conducted among 419 randomly selected healthcare personnel to collect sociodemographic, individual-level, community-level, and health system-level data, including vaccine uptake. Multivariable logistic regression analysis was performed to assess determinants of COVID-19 vaccine hesitancy at a 95% confidence level. COVID-19 vaccine hesitancy was found in 105 (25.1%) of respondents. Increased odds of vaccine hesitancy were associated with having 6-10 years of work experience (AOR = 3.43 95% CI = 1.44-8.18), being a midwife (AOR = 2.72 95% CI = 1.15-6.46), belief that vaccination does not guarantee protection against re-infection (AOR = 5.21 95% CI = 1.79-15.22), fear of long-term effects of COVID-19 (AOR = 2.14 95% CI = 1.18-3.86), perception of increased adverse effects among vaccinated individuals (AOR = 2.79 95% CI = 1.37-5.66), and community perception of long-term health effects of vaccination (AOR = 2.69 95% CI = 1.26-5.78). Awareness that health facilities were available to manage adverse effects reduced the odds of hesitancy (AOR = 0.23 95% CI = 0.12-0.43). Our study found that one in four healthcare personnel in the Volta Regional Hospital reported hesitancy toward receiving the COVID-19 vaccine. Targeted risk communication and confidence-building strategies tailored to midwives and healthcare workers with longer years of service, including interventions aimed at improving perceptions of vaccine efficacy and safety, may enhance COVID-19 vaccine uptake.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.