Evidence map›Paper›PMID 40966189›Full record

ArticleThe American journal of case reports2025

Gestational Gigantomastia in Multiparity: Successful Management with Bilateral Reduction and Free Nipple Grafts.

Ebtesam Almajed, Rana Alkhelaif, Saud Alrasheedi, Mishal D Alshammari

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ebtesam AlmajedDepartment of Clinical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Rana AlkhelaifDepartment of General Surgery, Security Forces Hospital, Riyadh, Saudi Arabia.
Saud AlrasheediDepartment of General Surgery, Security Forces Hospital, Riyadh, Saudi Arabia.
Mishal D AlshammariMedical Burn Unit and Plastic Surgery Department, Security Forces Hospital, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Gestational gigantomastia is a rare but benign diffuse enlargement of one or both breasts during pregnancy. This report describes the case of a 36-year-old woman with a history of previous pregnancies who presented with back pain associated with bilateral massive breast enlargement that was managed with breast reduction surgery. CASE REPORT A 36-year-old woman, gravida 4 para 3+1, presented 6 months postpartum with significant bilateral breast enlargement, shoulder numbness, and back pain. She was not breastfeeding, and her symptoms began in the second trimester of her fourth pregnancy. There was no evidence of overlying skin changes. Breast length from the sternal notch to the nipple was measured on the right breast at 50 cm and the left at 52 cm. A multidisciplinary team was involved, and the patient underwent bilateral breast reduction with free nipple grafts. A total of 5.150 kg of right breast tissue was excised, measuring 38.0×32.0×8.0 cm. Similarly, 5.530 kg of left breast tissue was excised, measuring 36.0×30.0×9.0 cm, for a total of 10.68 kg of breast tissue. Histopathological investigation confirmed benign breast tissue with fibrocystic changes, with no signs of malignancy. Her postoperative recovery was uneventful, with complete resolution of musculoskeletal symptoms and satisfactory aesthetic outcomes. CONCLUSIONS Gestational gigantomastia requires a multidisciplinary approach. This case highlights its potential to occur in later pregnancies, even without prior history, and demonstrates that bilateral breast reduction with free nipple grafts can offer effective symptom relief and favorable cosmetic outcomes. Preoperative counseling and individualized treatment planning are essential to optimize patient outcomes.

Indexed as

BreastHypertrophyMammaplastyNipplesPregnancy ComplicationsAdultFemaleHumansPregnancy

Identifiers

PMID40966189
PMCPMC12456090

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