Evidence map›Paper›PMID 40966078›Full record

ArticleCell reports2025

Neural dynamics in superior colliculus of freely moving mice.

Shelby L Sharp, Jhoseph Shin, Dylan M Martins, Keaton Jones, Cristopher M Niell

Abstract read
In one paragraph

Article in Cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Visual Motion Processing in The Tree Shrew Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shelby L SharpInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR 97403, USA.
Jhoseph ShinInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR 97403, USA.
Dylan M MartinsGraduate Program in Dynamical Neuroscience, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Keaton JonesInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR 97403, USA.
Cristopher M NiellInstitute of Neuroscience and Department of Biology, University of Oregon, Eugene, OR 97403, USA. Electronic address: cniell@uoregon.edu.

Funding

Cortical visual processing for navigationRF1NS121919 · NINDS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOARD, MICHAEL, NIELL, CRISTOPHER M · 2021 to 2021
$2.8M
The interaction of cortical and subcortical processing in natural sensory behaviorRF1NS127305 · NINDS · UNIVERSITY OF OREGON · PI NIELL, CRISTOPHER M, WEHR, MICHAEL · 2022 to 2024
$1.8M
The interaction of cortical and subcortical processing in natural sensory behaviorR01NS127305 · NINDS · UNIVERSITY OF OREGON · PI Cristopher M Niell, Michael Wehr · 2025 to 2026
$1.2M
The Impact of Natural Locomotion on Visual ProcessingF31EY034792 · NEI · UNIVERSITY OF OREGON · PI SHARP, SHELBY L · 2023 to 2024
$95k
NEI NIH HHS F31 EY034792NINDS NIH HHS R01 NS127305NINDS NIH HHS RF1 NS121919NINDS NIH HHS RF1 NS127305
6 · The paper itself

Abstract

Vision is an active process that depends on head and eye movements to explore the visual environment. Superior colliculus (SC) is known for its role in both generating these movements and processing visual information, but has not been studied extensively during free movement. To determine the impact of active vision on neural dynamics in mouse SC, we recorded neural activity across the depth of SC during free movement while simultaneously recording eye and head position. We show that superficial SC neurons respond to visual input following gaze-shifting saccadic movements, with a coarse-to-fine progression related to that observed in primary visual cortex (V1). On the other hand, activity in deep SC neurons corresponds to the motor component of gaze shifts, primarily for head movements rather than eye movements. Our results highlight the diverse roles of SC during active vision, while also revealing distinct differences in visual processing between SC and V1.

Indexed as

NeuronsSuperior ColliculiAnimalsEye MovementsHead MovementsMaleMiceMice, Inbred C57BLPrimary Visual CortexSaccadesactive visionCP: Neuroscienceeye movementssensorimotor integrationsuperior colliculus

Identifiers

PMID40966078
PMCPMC12987560

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.