Evidence map›Paper›PMID 40965979›Full record

ArticleJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2026

S2, S3, and S4 Sacral Dermatomal Evoked Potentials: Technical Parameters and Normative Values.

Prasad Malladi, Llwyd Orton, Sara Simeoni, Jalesh Panicker

Abstract read
In one paragraph

Article in Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Prasad MalladiUCL Institute of Neurology-Brain Repair and Rehabilitation, London, United Kingdom.ORCID 0000-0002-7480-3442
Llwyd OrtonDepartment of Life Sciences, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom .
Sara SimeoniUCL Institute of Neurology-Brain Repair and Rehabilitation, London, United Kingdom.
Jalesh PanickerUCL Institute of Neurology-Brain Repair and Rehabilitation, London, United Kingdom.

Funding

National School of Healthcare Science HSST 2018-19
6 · The paper itself

Abstract

purposeThe existing literature on the sacral dermatomal evoked potentials (dSEPs) is limited. This study aims to develop stimulating parameters and establish normative values for S2, S3, and S4 sacral dermatomes in healthy adult populations.

methodsTwenty healthy adult volunteers were enrolled in the study. The study was ethically approved, and written consent for participation was provided. All participants underwent tibial, pudendal, S2, S3, and S4 dSEPs. Stimulating and recorded parameters were established for all evoked potentials. P40 latency, amplitude, and interpeak parameters were calculated for each waveform. A comparison was made between tibial, pudendal somatosensory evoked potentials, and all sacral dSEPs. Normative values were generated for sacral dSEPs based on various height, age, and Body Mass Index (BMI) parameters.

resultsThe sacral dSEPs were well tolerated and recorded in all participants. S2 latency was mildly influenced by age and height, while S3 and S4 latencies were unaffected by age or height. BMI does not affect the S2 and S3 latencies but mildly affects the S4 latency. Sacral dSEP latencies were comparable with pudendal SEPS but not with the tibial somatosensory evoked potential.

conclusionsThe S2, S3, and S4 sacral dSEPs can be used as diagnostic tools to evaluate sacral nerve lesions such as cauda equina syndrome and Tarlov cysts, complementary to pudendal and tibial somatosensory evoked potentials.

Indexed as

Evoked Potentials, SomatosensorySacrumAdultElectric StimulationElectroencephalographyFemaleHumansMaleMiddle AgedReference ValuesYoung AdultCauda equina syndromeNormative valuesPudendal SEPSacral dermatomal evoked potentialsTarlov cystsTibial SEP

Identifiers

PMID40965979
PMCPMC13124256

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.