ArticleClinical hemorheology and microcirculation2025
Contrast-enhanced ultrasound perfusion quantification of solid liver lesions: First intraoperative characterization of tumor microvascularization.
Article in Clinical hemorheology and microcirculation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
AimAim of the study was to differentiate solid liver lesions according to their microvascularization. Therefore, we analyzed perfusion using time intensity curves (TIC) measured during contrast-enhanced intraoperative ultrasound (CE-IOUS).Material and MethodsData of 40 patients who underwent hepatic surgery with the diagnosis of hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCC), or liver metastases (LM) were retrospectively collected. CE-IOUS was performed using a linear multifrequency T-probe connected to a high-resolution device. Digital Imaging and Communications in Medicine (DICOM) loops were recorded, and TIC were analyzed for time to peak (TTP) and area under the curve (AUC) in tumor center, margin and reference tissue.ResultsAnalyses of the tumor center revealed significant higher AUC in HCC lesions than in CCC (
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