Evidence map›Paper›PMID 40965748›Full record

ArticleTropical animal health and production2025

Effects of oral herbal powder supplements on the adaptive capabilities of heat stressed Kenguri sheep based on changes in physiological and molecular response.

E Binuni Rebez, C Devaraj, J Ninan, M V Silpa, S Venkatesa Perumal, A Sahoo, F R Dunshea, V Sejian

Abstract read
PubMed Publisher
In one paragraph

Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

E Binuni RebezCentre for Climate Resilient Animal Adaptation Studies, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bangalore, 560030, India.
C DevarajCentre for Climate Resilient Animal Adaptation Studies, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bangalore, 560030, India.
J NinanRajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry, 605009, India.
M V SilpaRajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry, 605009, India.
S Venkatesa PerumalRajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry, 605009, India.
A SahooCentre for Climate Resilient Animal Adaptation Studies, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bangalore, 560030, India.
F R DunsheaSchool of Agriculture, Food and Ecosystem Sciences, Faculty of Science, The University of Melbourne, Parkville, Melbourne, VIC, 3010, Australia.
V SejianCentre for Climate Resilient Animal Adaptation Studies, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bangalore, 560030, India. drsejian@gmail.com.ORCID http://orcid.org/0000-0002-8224-4521

Funding

Indian Council of Agricultural Research Indian Council of Agricultural Research
6 · The paper itself

Abstract

A study was designed to establish the effect of heat stress on the adaptive capability of Kenguri sheep and to test the efficacy of herbal powder supplement for relieving heat stress in this breed. The study was carried out for a period of sixty days in twenty-four one-year-old Kenguri ewes which were randomly distributed into 4 different groups with six animals each as follows; KC (n = 6; Kenguri Control), KHS (n = 6; Kenguri Heat Stress), KCS (n = 6; Kenguri Control herbal Supplement) and KHSS (n = 6; Kenguri Heat Stress herbal Supplement). The results on temperature-humidity index (THI) indicated that comfort condition was provided for KC and KCS while severe heat stress condition was experienced by KHS and KHSS groups. Heat stress significantly increased the respiratory rate (RR), pulse rate (PR) and rectal temperature (RT). Further, heat stress also significantly upregulated the Heat Shock Transcription Factor 1 (HSF1), Heat Shock Protein 27 (HSP27), HSP70, HSP90 and HSP110. These results indicate that RR, PR, RT, HSF1, HSP27, HSP70, HSP90, and HSP110 can serve as reliable indicators for quantifying heat stress response in Kenguri sheep. In addition, the results also established the heat stress-relieving effects of herbal supplements as reflected by the significantly reduced physiological responses recorded and significantly downregulated all the genetic traits studied. Thus, it could be concluded that the herbal supplements used in the study was found to have effective potential to reduce the adverse impacts of heat stress in Kenguri sheep.

Indexed as

Dietary SupplementsHeat-Shock ResponseHeat Stress DisordersSheep, DomesticAnimalsBody TemperatureFemaleHeat-Shock ProteinsHot TemperaturePowdersSheepHeat-Shock ProteinsPowdersAdaptationHeat stressHerbal productHspsSheepTHI

Identifiers

PMID40965748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.