Evidence map›Paper›PMID 40965616›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Schaalia cardiffensis: an infrequent etiology of empyema with community-acquired pneumonia.

Kai Wu, Qingyao Li, Wei Wang, Lei Wang, Shuxia Wang

Abstract readCase Reports
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai WuClinical Laboratory, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu, China.
Qingyao LiDepartment of Radiology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Wei WangDepartment of Cardiothoracic Surgery, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Lei WangClinical Laboratory, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu, China.
Shuxia WangClinical Laboratory, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, Jiangsu, China. wsx0518@126.com.

Funding

the National Natural Science foundation of China 82202364
6 · The paper itself

Abstract

Schaalia infections are uncommon, with Schaalia cardiffensis infections being exceptionally rare. A 66-year-old, penicillin-allergic female presented with fever, cough and purulent sputum. Chest computed tomography revealed bilateral pneumonia, right loculated empyema and right lower lobe atelectasis. Initial drainage cultures identified only Streptococcus oralis, but subsequent anaerobic enrichment and 16 S rRNA gene sequencing confirmed S. cardiffensis, an obligate anaerobe. Due to absent susceptibility data, we established initial antimicrobial susceptibility profile for S. cardiffensis. Successful management was achieved using alternative antibiotics combined with percutaneous drainagein. This first Chinese case of an empyema co-infected with S. cardiffensis and S. oralis highlights diagnostic challenges and provides crucial susceptibility guidance.

Indexed as

Community-Acquired InfectionsEmpyemaPneumonia, BacterialAgedAnti-Bacterial AgentsCommunity-Acquired PneumoniaFemaleHumansMicrobial Sensitivity TestsRNA, Ribosomal, 16STomography, X-Ray ComputedAnti-Bacterial AgentsRNA, Ribosomal, 16SCommunity-acquired pneumoniaEmpyemaInitial antimicrobial susceptibility profileSchaalia cardiffensis

Identifiers

PMID40965616

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.