Evidence map›Paper›PMID 40965615›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

The possibility of Escherichia coli transmission from pregnant women to the neonates.

Dongmiao Zhang, Xiaoling Ge, Yajuan Wang, Wei Gao, Yijun Ding, Jinjing Zhang

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Research Progress on perinatalFrontiers in microbiology · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongmiao ZhangDepartment of Neonatology, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China.
Xiaoling GeDepartment of Neonatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Yajuan WangDepartment of Neonatology, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, Beijing, China. cxswyj@vip.sina.com.
Wei GaoLaboratory of Microbiology, Beijing Children's Hospital, Beijing Pediatric Research Institute, Capital Medical University, Beijing, China.
Yijun DingDepartment of Neonatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Jinjing ZhangDepartment of Neonatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.

Funding

Beijing Nova Programme Interdisciplinary Cooperation Project 20240484724High-level Public Health Technical Personnel Construction Project of Beijing Municipal Health Commission Academic leader -03-02National Natural Science Foundation of China 81872676Natural Science Foundation of Beijing Municipality 7232009
6 · The paper itself

Abstract

objectiveTo assess the homology of Escherichia coli between pregnant women and neonates and to identify the vertical transmission risk factors. STUDY

designPregnant women in 35-37 gestational weeks who underwent prenatal checkups between May 1st, 2015, and April 30th, 2016 were screened for Escherichia coli. Paired swabs from pregnant women and neonates were collected to evaluate the vertical transmission rate. Drug resistance, Multi-locus Sequence Typing, and potential risk factors were acquired to evaluate the homology and risk factors. Multiple logistic regression was used to account for potential confounders and evaluate the predictive ability of variables.

resultsThere were 201 (42.5%) positive swabs from pregnant women and 27 (5.7%) from neonates. Escherichia coli vertical transmission rate was 22 (11.0%, 95% CI 6.7%-15.3%). The most common ST was ST1193. Age of pregnant women (OR 1.19, 95% CI 1.06-1.34), time of premature rupture of membranes (OR 1.09, 95% CI 1.01-1.18), time of prenatal antibiotics use (OR 0.87 95% CI 0.74-0.98), and drug-resistant categories (OR 1.42 95% CI 1.00-2.07) were identified as significant factors. The predictive model achieved an area under the curve of 0.795 (95% CI: 0.683-0.908) and 0.743 (95% CI: 0.628-0.859) for the model of 10 factors and 4 factors, respectively. Escherichia coli positivity increases the likelihood of neonate hospitalization.

conclusionThe strong homology of Escherichia coli between pregnant women and neonates indicates the potential transmission of pathogenic strains, which should be screened and managed.

Indexed as

Escherichia coliEscherichia coli InfectionsInfectious Disease Transmission, VerticalPregnancy Complications, InfectiousAdultAnti-Bacterial AgentsFemaleHumansInfant, NewbornMultilocus Sequence TypingPregnancyRisk FactorsYoung AdultAnti-Bacterial AgentsAntibiotic resistanceEscherichia coliMulti-locus sequence typingNeonatePregnant womenVertical transmission

Identifiers

PMID40965615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.