ArticleJournal of assisted reproduction and genetics2025
Beyond oocyte quantity: the paradoxical role of poor ovarian response in live birth outcomes among endometriosis patients undergoing IVF/ICSI-ET.
Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo evaluate the impact of poor ovarian response (POR) on live birth outcomes in endometriosis patients undergoing IVF/ICSI-ET, despite the expected association between reduced oocyte yield and poorer prognosis.
methodsPatients were divided into two groups as endometriosis group (n = 55) and tubal factor group (n = 107). The primary outcomes included clinical pregnancy rate, live birth rate per embryo transfer cycle, and cumulative live birth rate. Secondary outcomes were controlled ovarian hyperstimulation (COH) results and embryo parameters.
resultsThe incidence rate of POR increased significantly in endometriosis group (18.9% vs. 5.60%, P < 0.05). Similarly, the number of oocytes retrieved, the number of D3 high quality embryos, and the number of available embryos were fewer in endometriosis group (P < 0.05). However, total number of available embryos, clinical pregnancy rates per transfer cycle, live birth rates per transfer cycle, and cumulative birth rate were found to be similar in both groups (P > 0.05). The presence of POR was found to have no significant impact on the cumulative live birth rate among patients with endometriosis.
conclusionsWhile linked to fewer oocytes per cycle, POR does not predict poorer IVF/ICSI-ET outcomes in endometriosis patients. Patient age, not POR or endometriosis itself, is the primary determinant of live birth success. This study challenges the conventional emphasis on oocyte quantity, advocating for a paradigm shift toward individualized, quality-focused ART strategies in endometriosis-related infertility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.