Evidence map›Paper›PMID 40965561›Full record

ArticleDigestive diseases and sciences2026

Impact of Periampullary Diverticulum on ERCP Outcomes and Recurrence of Common Bile Duct Stones.

Xiaoxi Xie, Yanni Li, Yonghao Chen, Chong Geng, Yaoyu Guo, Xiao Li, Chunhui Wang

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Article in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Xiaoxi Xie *Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Yanni Li *Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Yonghao ChenDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Chong GengDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Yaoyu GuoDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Xiao LiDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Chunhui WangDepartment of Gastroenterology and Hepatology, West China Hospital of Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China. wangch@scu.edu.cn.

Funding

Sichuan Science and Technology Program No. 2023YFS0281
6 · The paper itself

Abstract

purposeThis study was aimed to investigate the impact of periampullary diverticulum (PAD) on endoscopic retrograde cholangiopancreatography (ERCP) procedures and the recurrence of common bile duct stones (CBDS).

methods830 CBDS cases with native papilla were finally enrolled in the study, including 239 cases with PAD (type I, type II, and type III). Procedures and complications of ERCP were compared between the two groups. The patients with successful stone removal were followed up every 6 months until December 31, 2023.

resultsThe successful cannulation rate in the PAD group (96.7%) and type I PAD group (76.9%) was lower than that in the non-PAD group (99.2%). PAD was associated with a wider bile duct diameter, larger stone size, and a higher rate of cannulation with double guidewires, endoscopic sphincterotomy combined with endoscopic papillary balloon dilation and mechanical lithotripsy during the ERCP procedure. The incidence of complications did not differ between the two groups. Multivariate analysis revealed that PAD (OR = 3.265, 95%CI: 1.854-5.751) was an independent risk factor for the recurrence of CBDS.

conclusionPAD, especially type I PAD, may impact ERCP cannulation success rates. Additionally, PAD increases the complexity of stone extraction and is associated with CBDS recurrence.

Indexed as

Common bile duct stone (CBDS)Endoscopic retrograde cholangiopancreatography (ERCP)Periampullary diverticulum (PAD)Recurrence of bile duct stoneRisk factor

Identifiers

PMID40965561

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