Evidence map›Paper›PMID 40965390›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2026

The Protective Impact of Social Support on the Cascade Rates Between Internalizing Problems and Alcohol Misuse in Adolescence.

Laila Volpe, Daniel J O Roche, Katherine T Foster

Abstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laila VolpeUniversity of Washington, Department of Psychology, Seattle, Washington. Electronic address: lvolpe@uw.edu.
Daniel J O RocheUniversity of Maryland Baltimore, Department of Psychiatry, Maryland Psychiatric Research Center, Baltimore, Maryland.
Katherine T FosterUniversity of Washington, Department of Psychology, Seattle, Washington; University of Washington, Department of Global Health, Seattle, Washington.

Funding

Sex Differences in Autonomic Nervous System Function and Depression Across AdolescenceU01AA021696 · NIAAA · SRI INTERNATIONAL · PI Fiona C Baker · 2012 to 2026
$12.2M
NCANDA: Data Analysis Resource - Uploading Legacy Data to NDAU24AA021697 · NIAAA · STANFORD UNIVERSITY · PI Adolf Pfefferbaum, Kilian Maria Pohl · 2016 to 2026
$12.2M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: San DiegoU01AA021692 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Susan F. Tapert · 2012 to 2026
$11.8M
NCANDA Research Project Site: DukeU01AA021681 · NIAAA · DUKE UNIVERSITY · PI DAVID B. GOLDSTON · 2012 to 2026
$9.8M
The TEEN Study: The Impact of Adolescent Drinking on Connectivity in the BrainU01AA021691 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Angelica Marie Morales, Bonnie J. Nagel · 2012 to 2026
$8.5M
NCANDA Research Project Site: University of Pittsburgh (NCANDA-PITT)U01AA021690 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN B. CLARK, BEATRIZ LUNA · 2012 to 2026
$7.6M
National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA): Administrative ResourceU24AA021695 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, Susan F. Tapert · 2016 to 2026
$6.0M
N-CANDA: DATA ANALYSIS COMPONENTU01AA021697 · NIAAA · SRI INTERNATIONAL · PI PFEFFERBAUM, ADOLF, POHL, KILIAN MARIA · 2012 to 2015
$3.6M
National Consortium on Alcohol and NeuroDevelopment in Adolescence: AdminU01AA021695 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, SANDRA A, TAPERT, SUSAN F · 2012 to 2015
$2.1M
Development of minocycline as a neuroimmune therapy for alcohol use disorderK01AA026005 · NIAAA · UNIVERSITY OF MARYLAND BALTIMORE · PI ROCHE, DANIEL · 2017 to 2021
$925k
Using Advanced Methodologies to Investigate the Effect of Social Influences on Alcohol Use Across DevelopmentF31AA031154 · NIAAA · UNIVERSITY OF WASHINGTON · PI Laila Volpe · 2024 to 2026
$149k
NIAAA NIH HHS F31 AA031154NIAAA NIH HHS K01 AA026005NIAAA NIH HHS U01 AA021681NIAAA NIH HHS U01 AA021690NIAAA NIH HHS U01 AA021691NIAAA NIH HHS U01 AA021692NIAAA NIH HHS U01 AA021695NIAAA NIH HHS U01 AA021696NIAAA NIH HHS U01 AA021697NIAAA NIH HHS U24 AA021695NIAAA NIH HHS U24 AA021697
6 · The paper itself

Abstract

purposeAlcohol misuse (i.e., frequent, heavy drinking) and internalizing problems (i.e., anxiety, depression) typically manifest in adolescence. Both follow cascading trajectories where presence of one confers risk for the other. Delaying or preventing the cascade allows more time and opportunity to address symptoms before consequences accumulate and disrupt development. One candidate moderator for their cascading trajectories is social support, which is independently negatively associated with both alcohol misuse and internalizing problems. We tested whether social support affects bidirectional cascade rates between alcohol misuse and internalizing problems from adolescence through adulthood.

methodsTime-to-event analysis was applied to 7 years of longitudinal National Consortium on Alcohol and NeuroDevelopment in Adolescence data (n = 730, 51.23% female, M

resultsSocial support delayed the cascade rate (i.e., months to event) from each alcohol misuse marker to first internalizing episode (M DISCUSSION: Social support delays cascade rates triggered by alcohol misuse markers and first internalizing episode and may have long-term protective benefits, especially for boys. Targeted social support prevention efforts at ages of onset may prevent later alcohol misuse and internalizing problems. Critically, future research must identify what factors delay cascading trajectories in girls.

Indexed as

Adolescent BehaviorAlcoholismAnxietyDepressionSocial SupportUnderage DrinkingAdolescentFemaleHumansLongitudinal StudiesMaleYoung AdultAdolescentDepressionInternalizingRisk factorsSocial supportYoung adult

Identifiers

PMID40965390
PMCPMC12453876

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.