Evidence map›Paper›PMID 40965242›Full record

ReviewJournal of bacteriology2025

Breaking the silence-role of MucR as a virulence determinant in

Ian S Barton, Connor B Cribb, Beatriz Tartilán-Choya, Graham J Bitzer, Jodi Ogle, Neil Garza Hernandez, Daniel W Martin, Nieves Vizcaíno, Xindan Wang, Ilaria Baglivo and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ian S BartonDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.ORCID 0000-0002-0461-0522
Connor B CribbDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Beatriz Tartilán-ChoyaDepartment of Microbiology and Genetics, University of Salamanca, Salamanca, Spain.
Graham J BitzerDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Jodi OgleDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Neil Garza HernandezDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Daniel W MartinDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.
Nieves VizcaínoDepartment of Microbiology and Genetics, University of Salamanca, Salamanca, Spain.
Xindan WangDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0001-6458-180X
Ilaria BaglivoDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Caserta, Italy.
R Martin RoopDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.ORCID 0000-0003-2101-6928

Funding

Physicochemical properties driving membraneless organelle assembly in bacteriaR01GM143182 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BITEEN, JULIE, MEYER, ANNE SARA · 2021 to 2024
$2.4M
Determining the molecular basis of gene silencing by MucR and defining its role in Brucella virulenceR01AI172822 · NIAID · EAST CAROLINA UNIVERSITY · PI ROY M ROOP · 2023 to 2026
$2.3M
How bacterial SMC complexes organize chromosomes (Equipment Supplement)R01GM141242 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI WANG, XINDAN · 2021 to 2025
$1.8M
Role of a UPP-like exopolysaccharide in Brucella virulenceR21AI148132 · NIAID · EAST CAROLINA UNIVERSITY · PI ROOP, ROY M · 2020 to 2021
$401k
MCIN/AEI/10.13039/501100011033 PID2019-107601RB-C33National Institute of Allergy and Infectious Diseases R01AI172822, R21AI148132National Science Foundation 2022049NIAID NIH HHS R01 AI172822NIAID NIH HHS R21 AI148132NIGMS NIH HHS R01 GM141242NIGMS NIH HHS R01GM141242, R01GM143182NIGMS NIH HHS R01 GM143182
6 · The paper itself

Abstract

The Zn finger protein MucR is an H-NS-like protein that serves as a gene silencer and nucleoid-structuring protein in the α-proteobacteria. MucR is also an essential virulence determinant in

Indexed as

Bacterial ProteinsBrucellaGene Expression Regulation, BacterialVirulence FactorsAnimalsBrucellosisHumansVirulenceBacterial ProteinsVirulence FactorsBrucellaH-NS-like proteinMucRnucleoid-associated proteinvirulence

Identifiers

PMID40965242
PMCPMC12548446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.