SynthesisClinical microbiology reviews2025
Optimized use and performance of culture for periprosthetic joint infection diagnosis: a comprehensive literature review.
Synthesis in Clinical microbiology reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Editorial for the Special Issue "Challenges of Biofilm-Associated Bone and Joint Infections".Microorganisms · 2026Article
- Quantification of Sonicated Implants from Patients with Osteoarticular Implant Infections.Antibiotics (Basel, Switzerland) · 2026Article
- Rapid molecular culture versus conventional culture for periprosthetic joint infection: diagnostic performance and clinical relevance.Journal of bone and joint infection · 2026Article
- Current Concepts in Periprosthetic Joint Infection: Modern Biomarkers, Microbiome Insights, Molecular Diagnostics, and Emerging Prevention Strategies.Orthopedic research and reviews · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SUMMARYPeriprosthetic joint infection (PJI) is a significant complication of arthroplasty. Implicit in the diagnosis of PJI is the presence of organisms in what should be a sterile milieu. Given limits to culture-based PJI diagnosis, optimal utilization of culture in the diagnostic approach to PJI needs clarification. Culture is important in confirming a PJI diagnosis and characterizing the infecting microorganism(s) to inform management. As part of the development of a unified definition of PJI (by a group representing multiple scientific societies), a systematic review was performed to inform the role of culture in the definition of PJI. In addition, a comprehensive review on synovial fluid and periprosthetic tissue collection for culture, and associated culture methodology and results interpretation, was performed to inform best practices. Gaps in the literature were identified to develop research priorities.
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Registered trials
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