ReviewMini reviews in medicinal chemistry2025
Revolutionizing Diabetes Treatment with Insulin-loaded Nanoparticles.
Review in Mini reviews in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is a disease characterised by elevated blood glucose levels, with its major subtypes being type 1 (immune-mediated) and type 2 (lifestyle-related) diabetes. Medical treatment for diabetes requires patients to perform subcutaneous insulin injections since oral insulin faces problems with gastric breakdown. Nano-sized insulin delivery systems show great potential for oral usage because they protect the insulin molecule from enzymatic breakdown and enhance its absorption rates through the digestive system. The review article investigates the utilisation of insulin- loaded nanoparticles as an advanced treatment method for diabetes management. The data evaluates insulin-loaded nanoparticles for their impact on stability enhancement as well as their protective functions and improved oral bioavailability potential. The research reviewed the relevant literature on insulin-loaded nanoparticles as a treatment method for diabetes. The research articles were obtained through databases including ScienceDirect, Scopus, PubMed and Google Scholar. Studies about incorporating insulin with nanoparticles and their bioavailability features and therapeutic potential were analysed. The review demonstrates that insulin-loaded nanoparticles markedly improve insulin stability, bioavailability, and absorption, overcoming the challenges associated with oral insulin delivery. Diverse nanoparticle compositions, encompassing polymeric and lipid-based carriers, exhibit encouraging outcomes in preclinical investigations. Despite existing limitations in large-scale production and clinical application, nanotechnology presents a revolutionary method for diabetes treatment. Additional research and clinical studies are necessary to validate insulin-loaded nanoparticles as a feasible, patient-friendly substitute for traditional insulin therapy.
Indexed as
Identifiers
40965032What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.