ReviewCurrent drug targets2026
Therapeutic Potential of Scorpion Venom Proteins: Innovations in Cancer Treatment and Future Directions.
Review in Current drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is a significant human health concern due to its increasing mortality rate and profound impact on public health and healthcare systems. The cytotoxic, antiproliferative, immunosuppressive, and apoptogenic properties of scorpion venom proteins and peptides have been observed in various cancer cell lines. Therefore, the purpose of this study was to investigate the potential use of proteins derived from scorpion venom in cancer treatment. In this study, the effects of different scorpion venoms on transmembrane channels, the inhibition of angiogenesis, the inhibition of invasion and metastasis, the inhibition of proliferation, and the induction of apoptosis were investigated, as were their clinical applications in the treatment of hepatocellular carcinoma and breast, cervical, prostate, colorectal, and melanoma cancers. The results showed that various scorpion venoms can suppress cell growth, stimulate apoptosis, reduce tumor size, and enhance the immune response, thereby serving as alternative drugs for treating various types of cancers and their metastasis. This review suggests a positive association between scorpion venom (SV) proteins and the treatment of these cancers. Future research should focus on understanding the underlying mechanisms, identifying biomarkers to predict response, and exploring potential combination therapies to increase the efficacy of scorpion venom proteins in cancer treatment.
Indexed as
Identifiers
40965031What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.