Evidence map›Paper›PMID 40964953›Full record

ArticleWomen's health (London, England)

Implementing self-collection for primary human papillomavirus testing: Perspectives on implications for federally qualified health center patient populations.

Amanda Le, Liisa S Smith, Stephanie B Wheeler, Kara Giannone, MaryShell Zaffino, Jennifer Elston Lafata, Jennifer S Smith

Abstract read
In one paragraph

Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amanda LeDepartment of Public Health Leadership, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0009-0009-4670-3426
Liisa S SmithDepartment of Public Health Leadership, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Stephanie B WheelerDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kara GiannoneLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
MaryShell ZaffinoBlue Ridge Health, Hendersonville, NC, USA.
Jennifer Elston LafataLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Jennifer S SmithLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0002-1256-0422

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
Demonstration and Implementation of Self-Collection for HPV Testing in a Federally Qualified Health Center System (UH2/3 supplement)UH3CA202663 · NCI · BECTON, DICKINSON AND COMPANY · PI SMITH, JENNIFER SUSAN, WEIDEMAIER, KRISTIN · 2018 to 2020
$1.3M
Cytology-Free POC Cervical Cancer Diagnostics for Global HealthUH2CA202663 · NCI · BECTON, DICKINSON AND COMPANY · PI SMITH, JENNIFER SUSAN, WEIDEMAIER, KRISTIN · 2016 to 2017
$991k
NCI NIH HHS P30 CA016086NCI NIH HHS UH2 CA202663NCI NIH HHS UH3 CA202663NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

backgroundPrimary testing for high-risk human papillomavirus (HPV) via self-collection can increase cervical cancer screening rates. In the United States, federally qualified health center (FQHC) patients often have low incomes, lack health insurance, are medically underserved, and are screened less than the national average. Implementation of HPV self-collection can increase cervical cancer screenings among FQHCs.

objectivesTo assess the potential impact of implementing HPV self-collection with FQHC patients by considering perspectives of frontline clinical and administrative staff and leadership to identify patient-focused implementation considerations.

designThis qualitative study utilized focus groups and key informant interviews, and transcripts were analyzed using a coding-based thematic analysis. Emergent themes regarding self-collection implementation perspectives were mapped onto Consolidated Framework for Implementation Research constructs to identify potential facilitators and barriers to implementation for FQHC patient populations.

methodsParticipants from six FQHCs in North Carolina were identified. Forty-five clinical and administrative staff participated in focus groups. One chief executive officer, senior level administrator, chief medical officer, and clinical data manager from each FQHC (

resultsInterviewees indicated that HPV self-collection can be advantageous to patients who do not routinely visit the clinic due to socioeconomic and cultural barriers. Programs must consider these barriers and patient literacy to ensure proper self-collection utilization. For example, FQHC patients may benefit from illustrated instructions for proper self-collection procedures.

conclusionTailoring an HPV self-collection implementation to FQHC patient populations may be an important strategy for increasing screening.

Indexed as

Early Detection of CancerMass ScreeningPapillomavirus InfectionsSelf CareSpecimen HandlingUterine Cervical NeoplasmsAdultFemaleFocus GroupsHuman Papillomavirus VirusesHumansInterviews as TopicMiddle AgedNorth CarolinaPapillomaviridaeQualitative Researchcervical cancerfederally qualified health centershuman papillomavirusself-collection

Identifiers

PMID40964953
PMCPMC12446813

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.