ReviewCytoskeleton (Hoboken, N.J.)2026
TUBA4A: The Tale of an Unconventional Tubulin.
Review in Cytoskeleton (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- TUBA4A Pathogenic Variant Manifesting With Adulthood-Onset Genetic Myasthenic Syndrome, Myopathy, and Infertility.European journal of neurology · 2026Article
- TUBA4A: The Tale of an Unconventional Tubulin.Cytoskeleton (Hoboken, N.J.) · 2026Review
- Genetic Mutations and Non-Genomic Dysregulation in Human Preimplantation Embryo Arrest.International journal of molecular sciences · 2026Review
- Potential Biological Processes Related to Brain SLC13A5 Across the Lifespan: Weighted Gene Co-Expression Network Analysis from Large Human Transcriptomic Data.Brain sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Microtubules are highly adaptable cytoskeletal polymers whose dynamic nature supports a broad spectrum of cellular activities. Their dynamic behavior is regulated by an intricate network of factors, including tubulin isotypes and post-translational modifications. Together, these elements shape the properties of microtubules in response to both intrinsic and extrinsic cues. Within this regulatory landscape, the "tubulin code" has been proposed as a conceptual framework to explain how subtle molecular variations shape context-specific microtubule functions. Among mammalian α-tubulin isotypes, TUBA4A is characterized by the unique C-terminal tail, distinct biochemical behaviors, enriched expression in multiple tissues (e.g., in the central nervous system) and emerging roles in neurodegeneration. This review summarizes the molecular and physiological features of TUBA4A, highlights its potential contributions to normal neuronal function and neurological disorders, and offers perspectives for future studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.