Evidence map›Paper›PMID 40964734›Full record

ArticleHand (New York, N.Y.)2026

Secondary Carpal Tunnel Release After Surgical Fixation of the Distal Radius: A Case-Control Study.

Stella den Hengst, Koen Eppink, Navid Ghaderi, Krystle R Tuaño, Kyle R Eberlin, Abhiram R Bhashyam

Abstract read
In one paragraph

Article in Hand (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Stella den HengstMassachusetts General Hospital, Boston, USA.ORCID 0009-0006-7164-5430
Koen EppinkMassachusetts General Hospital, Boston, USA.
Navid GhaderiMassachusetts General Hospital, Boston, USA.
Krystle R TuañoMassachusetts General Hospital, Boston, USA.ORCID 0000-0003-2616-3652
Kyle R EberlinMassachusetts General Hospital, Boston, USA.ORCID 0000-0003-4427-2588
Abhiram R BhashyamMassachusetts General Hospital, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarpal tunnel syndrome (CTS) may occur after surgical fixation of a distal radius fracture (DRF) and can result in muscle atrophy and permanent nerve damage if untreated. Despite increased surgical treatments for DRFs, the frequency and risk factors for secondary carpal tunnel release (CTR) after DRF fixation remain unclear. This study aims to identify the frequency of secondary CTR after DRF fixation and factors associated with secondary release.

methodsAdult patients who underwent either a secondary CTR within 1 year after surgical fixation of the DRF (secondary release case group) or a concomitant CTR (concomitant release control group) between 2001 and 2023 were identified. Secondary release cases were matched 1:4 to concomitant release controls. Patient, diagnosis, and treatment characteristics were collected and analyzed. Multivariable logistic regression using backward selection was performed to identify risk factors for secondary CTR.

resultsOf 6612 surgically treated DRFs, 77 patients (1.2%) underwent secondary release within the first year, and 948 patients (14.3%) underwent concomitant release. Nerve compression symptoms before initial surgical fixation of the DRF were observed in 26 patients (33.8%). Multivariable logistic regression revealed that hypothyroidism and osteoporosis were statistically significant predictors for secondary CTR after surgical fixation of the DRF. The scores of Quick Disabilities of the Arm, Shoulder, and Hand and Patient-Reported Outcomes Measurement Information System (PROMIS)-Upper Extremity were clinically similar for both groups of patients.

conclusionOf all patients undergoing CTR within 1 year of DRF fixation, 92.5% underwent concomitant release, and 7.5% underwent secondary release. Patients diagnosed with hypothyroidism or osteoporosis were significantly more likely to undergo a secondary surgery for CTR.

Indexed as

Carpal Tunnel SyndromeDecompression, SurgicalFracture Fixation, InternalPostoperative ComplicationsRadius FracturesWrist FracturesAdultAgedCase-Control StudiesFemaleHumansLogistic ModelsMaleMiddle AgedOsteoporosisReoperationcarpal tunnel releasedistal radius fracturenerve compressionnerve decompressionsurgical fixation

Identifiers

PMID40964734
PMCPMC12446280

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.