Evidence map›Paper›PMID 40964710›Full record

Trial reportStroke2026

High-Dose Walking Booster Program Is Feasible for People After Stroke: A Phase II Randomized Trial.

Katharine Scrivener, Avanthi Elisha Ball, Catherine Dean, Joanne Glinsky, Louise Ada, Petra Graham, Johannah Campbell, Karen Felton, Natasha A Lannin

Abstract readRandomized Controlled TrialClinical Trial, Phase IIMulticenter Study
In one paragraph

Trial report in Stroke, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katharine ScrivenerDepartment of Health Sciences, Faculty of Medicine, Health and Human Sciences (K.S., A.E.B., C.D., J.C., K.F.), Macquarie University, Sydney, Australia.ORCID 0000-0003-0851-7023
Avanthi Elisha BallDepartment of Health Sciences, Faculty of Medicine, Health and Human Sciences (K.S., A.E.B., C.D., J.C., K.F.), Macquarie University, Sydney, Australia.
Catherine DeanDepartment of Health Sciences, Faculty of Medicine, Health and Human Sciences (K.S., A.E.B., C.D., J.C., K.F.), Macquarie University, Sydney, Australia.
Joanne GlinskyDiscipline of Physiotherapy, Faculty of Medicine and Health, University of Sydney, Australia (J.G., L.A.).
Louise AdaDiscipline of Physiotherapy, Faculty of Medicine and Health, University of Sydney, Australia (J.G., L.A.).ORCID 0000-0003-1369-5721
Petra GrahamSchool of Mathematical and Physical Sciences, Faculty of Science and Engineering (P.G.), Macquarie University, Sydney, Australia.ORCID 0000-0003-2890-2447
Johannah CampbellDepartment of Health Sciences, Faculty of Medicine, Health and Human Sciences (K.S., A.E.B., C.D., J.C., K.F.), Macquarie University, Sydney, Australia.
Karen FeltonDepartment of Health Sciences, Faculty of Medicine, Health and Human Sciences (K.S., A.E.B., C.D., J.C., K.F.), Macquarie University, Sydney, Australia.
Natasha A LanninDepartment of Neurosciences, Monash University and Allied Health, Alfred Health, Melbourne, Australia (N.A.L., K.S.).ORCID 0000-0002-2066-8345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaintaining walking ability in the long term after a stroke is challenging. Furthermore, access to ongoing physiotherapy is limited. This trial determined the feasibility of a clinical trial of a high-dose walking booster program (HiWalk) and measured clinical outcomes.

methodsA multisite, assessor-blinded pilot and feasibility randomized trial was conducted in Australia (June 2023 to July 2024). Participants had a stroke 6 months to 8 years prior and could walk unaided at 0.4 m/s to 1.0 m/s. The experimental group received HiWalk plus usual care, while the control group received usual care alone. HiWalk was group-based motor training to improve walking, 43 hours over 3 weeks. Feasibility outcomes included recruitment and retention. Clinical outcomes included walking speed (preferred and fast over 5 m, fast over 6 minutes), and self-efficacy at 1 and 6 months.

resultsEighty-two individuals were screened, and 47 participated: age 58 (SD, 16), time poststroke 2.7 years (SD, 2.1), and baseline fast walking speed 0.9 m/s (SD, 0.4). Feasibility outcomes: the HiWalk trial was feasible in terms of recruitment (refusal rate 27%), retention at 1 month (98%), adherence (mean 91% [SD 13] attendance once commenced), safety (minor adverse events 0.4/wk), and measurement (98% of data collected at 1 month). Clinical outcomes: at month 1, there was a beneficial effect on a 30-point self-efficacy scale (mean difference, 3.0 [95% CI, 0.1-5.9]). However, despite a small positive mean effect of HiWalk on fast walking speed (mean difference, 0.05 m/s [95% CI, -0.09 to 0.19]), there were no other significant between group differences. Exploratory analysis suggests the effect on walking speed for those not undertaking rehabilitation was 0.24 m/s (95% CI, 0.06-0.43) more than for those who were.

conclusionsThe HiWalk booster program was a feasible way to deliver mobility training in the community after stroke. Benefits in clinical outcomes were found for the subgroup of participants no longer undertaking rehabilitation. Therefore, future research should target this subpopulation. REGISTRATION: URL: https://www.anzctr.org.au; Unique identifier: ACTRN12623000316606.

Indexed as

Exercise TherapyStrokeStroke RehabilitationWalkingAdultAgedAustraliaFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsSelf EfficacyTreatment Outcomephysical therapyrecovery of functionself efficacystrokewalking

Identifiers

PMID40964710
PMCPMC12721604

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.