Evidence map›Paper›PMID 40964685›Full record

ArticleFrontiers in nutrition2025

Association between joint physical activity and alcohol intake and all-cause mortality in patients with cardiovascular disease: findings from NHANES 2007-2018.

Shiyang Zhang, Yeji Zhuo, Chunyan Zhu, Tong Zhou, Zongtao Wang, Jianyi Zheng, Tudi Li, Rong Chen, Dong Lin, Zhixin Xie and 3 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shiyang ZhangDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Yeji ZhuoDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Chunyan ZhuDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Tong ZhouDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Zongtao WangDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Jianyi ZhengDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Tudi LiDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Rong ChenDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Dong LinDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Zhixin XieDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Zhenyang FuDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Zhihuan ZengDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Kaitong ChenDepartment of Cardiology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Physical activity and alcohol consumption are both highly prevalent in many countries, while the evidence related to joint effect on physical activity and alcohol consumption on patients with cardiovascular disease (CVD) was still deficient. This study was aimed to investigate the association between joint moderate-to-vigorous physical activity (MVPA) and alcohol intake and all-cause mortality in patients with CVD. Methods: A total of 4,047 participants from the National Health and Nutrition Examination Survey (NHANES) with self-reported CVD history, exercise and alcohol consumption amounts were included this study. Participants were stratified into 12 groups by MVPA level (none/insufficient/sufficient) and alcohol intake (abstainer/light/moderate/heavy). Restricted cubic spline and Cox regression models assessed mortality associations. Results: MVPA showed an L-shaped association with mortality, while alcohol exhibited a U-shaped pattern. The lowest observed mortality risk occurred in patients with MVPA ≥150 min/week and alcohol consumption 8.4-15.4 drinks/week (HR = 0.348, 95% CI: 0.169-0.667). Comparably lower risk was seen with MVPA <150 min/week plus light alcohol intake (<8.4 drinks/week) (HR = 0.400, 95% CI: 0.267-0.588). Conclusion: Among patients with established CVD, any level of MVPA was associated with survival benefits. The greatest mortality reduction occurred with >150 min/week of MVPA alongside light to moderate alcohol consumption (<15.4 drinks/week). However, comparable survival benefits were observed with <150 min/week of MVPA when coupled with light alcohol intake. MVPA remains the cornerstone for mortality risk reduction in this population.

Indexed as

alcoholcardiovascular diseaselight drinkingNHANESphysical activity

Identifiers

PMID40964685
PMCPMC12436399

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.