ArticleJournal of conservative dentistry and endodontics2025
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of laser-activated and passive ultrasonic irrigation on apical sealing and dentinal tubule penetration of a bioceramic sealer: AnJournal of conservative dentistry and endodontics · 2026Article
- Effectiveness of Erbium: Yttrium-Aluminum-Garnet laser with side-firing spiral EndoTip and ethylenediaminetetraacetic acid on smear layer removal: A scanning electron microscopic study.Journal of conservative dentistry and endodontics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: Successful root canal treatment (RCT) depends on effective irrigant activation to enhance disinfection and minimize the risk of apical periodontitis. Laser-activated irrigation (LAI) has shown promise; however, its periapical safety remains to be fully evaluated. Aims: The aim of this study was to assess and compare the periapical safety of erbium:yttrium-aluminum-garnet (Er: YAG) and diode laser irrigation protocols with passive ultrasonic irrigation (PUI) during RCT. Settings and Design: This was a quantitative Methods: Sixty-six extracted human single-rooted teeth were standardized and fixed into a 96-well plate containing 300 μL of a pH indicator solution. Teeth were randomly allocated to three groups: PUI, diode laser, and Er: YAG laser. Irrigation with 5.25% sodium hypochlorite (NaOCl) was activated using the designated technique. Apical extrusion of NaOCl was quantified using ELISA-based spectrophotometry. Statistical Analysis Used: Kruskal-Wallis and Results: All groups showed apical extrusion. The Er: YAG group had significantly less extrusion than the diode and PUI groups ( Conclusions: Within the study's limitations, Er: YAG and diode LAI reduced apical NaOCl extrusion compared to PUI, indicating improved periapical safety. Further clinical studies are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.