Evidence map›Paper›PMID 40964633›Full record

ArticleJournal of conservative dentistry and endodontics2025

Antibacterial efficacy and molecular docking analysis of

Srilekha Jayakumar, Anbarasu Subramanian, S Sabarinathan, H Shalini, Bindu Meera John, R Saravanan

Abstract read
In one paragraph

Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Fermentation-Derived 6-Shogaol fromInternational journal of molecular sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Srilekha JayakumarDepartment of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kelambakkam, Affiliated to The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
Anbarasu SubramanianDepartment of Dental Surgery, Government Kallakurichi Medical College and Hospital, Kallakurichi, Affiliated to The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
S SabarinathanDepartment of Dental Surgery, Government Kallakurichi Medical College and Hospital, Kallakurichi, Affiliated to The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India.
H ShaliniDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Bindu Meera JohnDepartment of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth, Puducherry, India.
R SaravananDepartment of Conservative Dentistry and Endodontics, Tagore Dental College and Hospital, Rathinamangalam, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aim and Objectives: To evaluate the antimicrobial efficacy of Materials and Methods: Extracts were prepared by powdering freshly dried ginger and garlic, and the extraction process was done using a Soxhlet apparatus. Broth microdilution assay and microtiter plate assay of the ginger and garlic extracts were done for evaluating antibacterial activity. Gas chromatography-mass spectrometry analysis was done to identify phytochemical constituents present in extracts responsible for antibacterial action. Molecular docking was done to evaluate the interaction between phytoconstituents and the target protein (NanA) of Statistical Analysis: Statistical analysis was done by IBM SPSS version 30.0. One-way ANOVA test was used for intergroup comparison. Results: The minimum inhibitory concentration was determined to be 0.9 μg/mL for ZO and AS extracts. Both Ginger and Garlic extract showed a dose-dependent activity on Conclusion: Garlic and ginger extracts both showed better antibacterial activity against

Indexed as

Fusobacterium nucleatumgarlicgingermolecular dockingNanA

Identifiers

PMID40964633
PMCPMC12440328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.