Acoustic Analysis of Apraxia of Speech in a Japanese Patient With Nonfluent/Agrammatic Variant Primary Progressive Aphasia: A Case Study.

Narihiro Kodama, Akiko Miyazaki, Yuhei Kodani, Ryo Hatazoe, Kosei Hashimoto

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Narihiro KodamaDepartment of Speech - Language Pathology and Audiology, Faculty of Rehabilitation, Kawasaki University of Medical Welfare, Kurashiki, JPN.

Akiko MiyazakiRehabilitation Center, Kawasaki Medical School Hospital, Kurashiki, JPN.

Yuhei KodaniDepartment of Speech - Language Pathology and Audiology, Faculty of Rehabilitation, Kawasaki University of Medical Welfare, Kurashiki, JPN.

Ryo HatazoeDepartment of Rehabilitation, Kumamoto Health Science University, Kumamoto, JPN.

Kosei HashimotoDepartment of Speech, Language and Hearing Therapy, Faculty of Health Sciences, Mejiro University, Saitama, JPN.

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6 · The paper itself

Abstract

Apraxia of speech (AOS) is a motor speech disorder often observed in the nonfluent/agrammatic variant of primary progressive aphasia (nfvPPA). While acoustic analysis has proven useful in identifying AOS features in English speakers, data on Japanese speakers are limited. This study investigated the acoustic characteristics of AOS in a 70-year-old Japanese woman diagnosed with corticobasal syndrome and nfvPPA. Speech and neuropsychological assessments revealed typical AOS features. Acoustic measures included triangular vowel space area (tVSA), voice onset time (VOT), and speech duration. As a result, although tVSA was relatively preserved, both VOT and speech duration were prolonged. These findings suggest that VOT and speech duration may serve as effective acoustic markers for detecting AOS in Japanese, providing useful objective indicators for diagnosis and treatment planning.

Indexed as

acoustic analysisapraxia of speech (aos)nonfluent/agrammatic variant primary progressive aphasia (nfvppa)triangular vowel space area (tvsa)voice onset time (vot)

Identifiers

PMID40964563

DOI10.7759/cureus.90325

PMCPMC12440634

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