Evidence map›Paper›PMID 40964546›Full record

ArticleCureus2025

Incidence and Clinical Characteristics of Respiratory Sarcopenia in Community-Dwelling Older Adults: A Cross-Sectional Study.

Urara Chiba, Tomoyuki Morisawa, Yota Kunieda, Shoki Yusu, Kohei Kawamura, Tomokazu Takakura, Masakazu Saitoh, Kotaro Iwatsu, Tetsuya Takahashi, Toshiyuki Fujiwara

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Urara ChibaDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Tomoyuki MorisawaDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Yota KuniedaDepartment of Rehabilitation Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, JPN.
Shoki YusuDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Kohei KawamuraDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Tomokazu TakakuraDepartment of Rehabilitation Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo, JPN.
Masakazu SaitohDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Kotaro IwatsuDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Tetsuya TakahashiDepartment of Physical Therapy, Graduate School of Health Science, Juntendo University, Tokyo, JPN.
Toshiyuki FujiwaraDepartment of Physical Therapy, Faculty of Health Science, Juntendo University, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to determine the prevalence, characteristics, and associated factors of respiratory sarcopenia in community-dwelling older adults.

methodsThis cross-sectional study included 369 community-dwelling older adults aged 65 years and above, living in Koto-ku, Tokyo, Japan. Measurements included body composition, physical function (grip strength, walking speed, and 5 chair-stand, 5CS, test), physical activity (the International Physical Activity Questionnaire-Short Form), respiratory muscle strength (%Maximal Inspiratory Pressure, %MIP, and %Maximal Expiratory Pressure, %MEP), oral function (oral diadochokinesis, ODK; tongue pressure), cognitive function (Montreal Cognitive Assessment-Japanese), and health-related quality of life (the MOS 8-Item Short-Form Health Survey). Participants were classified into three mutually exclusive groups based on respiratory muscle strength and limb skeletal muscle mass. The Probable respiratory sarcopenia group (Probable group) included individuals with both reduced respiratory muscle strength (defined as both %MIP and %MEP values below 80%) and low limb skeletal muscle mass (defined as <7 kg/m² in men and <5.7 kg/m² in women, based on the Asian Working Group of Sarcopenia 2019). The Possible respiratory sarcopenia group (Possible group) included participants with reduced respiratory muscle strength alone but normal skeletal muscle mass. The Robust group comprised those with neither respiratory muscle weakness nor low skeletal muscle mass. The prevalence of each group was calculated separately. For further analysis, the Probable and Possible groups were combined into a single respiratory sarcopenia group, and the Robust group was used as the control. A t-test, Mann-Whitney U test, and chi-square test were used to compare the characteristics of each group. Logistic regression analysis was then performed to identify factors associated with the presence of respiratory sarcopenia.

resultsThe prevalence of Probable respiratory sarcopenia was 3.3%, and that of Possible respiratory sarcopenia was 33.3%. Compared with the Robust group, the respiratory sarcopenia group exhibited significantly poorer physical function, including grip strength, gait speed, 5CS performance, physical activity, and oral function. Additionally, cognitive function was significantly lower in the respiratory sarcopenia group. Significant factors associated with respiratory sarcopenia included grip strength, 5CS, moderate physical activity, tongue pressure, and fat-free mass.

conclusionThe prevalence of Probable respiratory sarcopenia and Possible respiratory sarcopenia among community-dwelling older adults was 3.3% and 33.3%, respectively. Respiratory sarcopenia was characterized by significantly lower physical function (grip strength, gait speed, and 5CS), physical activity, oral function (ODK and tongue pressure), and cognitive function. Furthermore, grip strength, 5CS score, moderate physical activity, and tongue pressure were identified as significant factors associated with respiratory sarcopenia, suggesting that it requires a comprehensive evaluation including physical function, physical activity, oral function, and cognitive function.

Indexed as

cognitive functioncommunity-dwelling older adultsoral functionrespiratory musclesarcopenia

Identifiers

PMID40964546
PMCPMC12439863

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.