ArticleCureus2025
Multimodal Imaging in the Diagnosis of Primary Aortic Epithelioid Angiosarcoma.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary malignant tumors of the aorta (PMTA) are rare, yet highly aggressive neoplasms associated with poor prognosis. The preoperative diagnosis of these tumors remains challenging, as conventional imaging modalities, including computed tomography (CT) and magnetic resonance imaging (MRI), frequently fail to distinguish PMTA from atherothrombotic lesions. This case highlighted the efficacy of multimodality imaging, particularly F-18 fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), in diagnosing PMTA, such as aortic intimal angiosarcomas. A 73-year-old male patient presented with a history of intermittent fever and persistently elevated inflammatory markers over a three-month period. Initial CT revealed a pedunculated intraluminal mass within the descending aorta, accompanied by multiple infarctions of the spleen and kidneys. No apparent contrast enhancement of the lesion was observed on CT. MRI demonstrated mildly high-signal intensity on T1- and T2-weighted images, without marked contrast enhancement. Cine MRI indicated tumor margin mobility, suggesting a dynamic lesion, rather than a fixed thrombus. FDG-PET/CT revealed abnormal hypermetabolic activity within the aortic lesion, with a maximum standardized uptake value of 10.8. Moreover, this modality identified distant metastases within the ribs and femoral head. The patient subsequently underwent descending aortic replacement surgery, and histopathological analysis confirmed the diagnosis of an epithelioid angiosarcoma. Despite postoperative chemotherapy, the patient died due to the progression of brain metastases. This case confirmed the essential role of FDG-PET/CT in distinguishing PMTA from atherothrombotic lesions. Due to the poor prognosis and aggressive nature of PMTA, early diagnosis through multimodal imaging is paramount in guiding appropriate clinical management and improving treatment outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.