ArticleCureus2025
Natural Pregnancy Following Oocyte Retrieval in a Luteal-Phase Progestin-Primed Ovarian Stimulation (PPOS) Protocol With Concurrent Blastocyst Cryopreservation: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ovarian stimulation is used in assisted reproductive technology to help infertile couples achieve pregnancy. Luteal-phase stimulation with progestin-primed ovarian stimulation (PPOS) is a practical approach, as it involves oral medication with fewer daily injections compared to gonadotropin-releasing hormone (GnRH) agonist or GnRH antagonist protocols. Unintended pregnancy during ovarian stimulation or after oocyte pick-up (OPU) is rare but possible. We present the case of a 38-year-old patient with secondary infertility, known to have endometriosis, chronic inflammatory demyelinating polyneuropathy, and low ovarian reserve. She initially underwent ovarian stimulation with an antagonist protocol, which was later switched to luteal-phase PPOS to improve synchronization. For ovulation induction to initiate luteal-phase stimulation, the patient received human chorionic gonadotropin (hCG). A pregnancy test performed during ovarian stimulation yielded a result consistent with exogenous hCG administration. On the day of OPU, a corpus luteum was observed in the right ovary, and two follicles were present in the left ovary. OPU resulted in the retrieval of one oocyte, which developed into a blastocyst and was subsequently cryopreserved. A natural pregnancy was detected by hCG testing 10 days after OPU, prompted by a delayed menstrual cycle and the corpus luteum observed during OPU. Transvaginal ultrasound confirmed an intrauterine pregnancy with a positive fetal heartbeat. This case highlights the importance of considering the possibility of pregnancy even after luteal-phase PPOS and OPU, taking into account both the patient's clinical context and laboratory findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.