ArticleInternational journal of clinical and experimental pathology2025
Comparative evaluation of β-glucan functional dressing and interferon-α2a plug for vaginal microecology restoration and HPV clearance in women with bacterial vaginosis or aerobic vaginitis.
Article in International journal of clinical and experimental pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo compare the effectiveness of β-glucan functional dressing and interferon-α2a (IFN-α2a) plug in promoting high-risk human papillomavirus (HR-HPV) clearance and restoring vaginal microecology in women with bacterial vaginosis (BV) or aerobic vaginitis (AV).
methodsThis prospective-retrospective study enrolled 44 women diagnosed with BV or AV. Participants were evaluated for vaginal ecological indicators including pH, cleanliness, hydrogen peroxide (H
resultsBoth groups were comparable at baseline. No adverse effects were reported. Post-treatment analysis showed that β-glucan dressing significantly improved markers of inflammation (LE, H
conclusionBoth β-glucan and IFN-α2a dressings were safe and showed clinical benefits in women with BV or AV and HR-HPV infection. However, β-glucan demonstrated superior outcomes in restoring vaginal microecology and enhancing HPV clearance. These findings suggest that β-glucan may serve as a more effective intravaginal immunomodulatory therapy. Further multicenter studies with larger samples are needed to confirm these results.
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