Evidence map›Paper›PMID 40964467›Full record

ArticleCureus2025

Posterior Approach Resection of Giant Schwannomas at the Craniovertebral Junction: A Case Series.

Glennie Ntsambi, Israël A Maoneo, Punga Ziko, Jean-Richard Kabongo, Simon Kutoloka, Chérubin Tshiunza, Larrey Kasereka Kamabu, Bienvenu Lebwaze, Raphael Chirimwami, Dieudonné Sanduku and 1 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Glennie NtsambiNeurosurgery, University of Kinshasa, Kinshasa, COD.
Israël A MaoneoNeurosurgery, University of Kisangani, Kisangani, COD.
Punga ZikoNeurosurgery, University of Kinshasa, Kinshasa, COD.
Jean-Richard KabongoNeurosurgery, University of Kinshasa, Kinshasa, COD.
Simon KutolokaNeurosurgery, University of Kinshasa, Kinshasa, COD.
Chérubin TshiunzaNeurosurgery, Centre Hospitalier Initiative Plus, Kinshasa, Kinshasa, COD.
Larrey Kasereka KamabuNeurosurgery, Catholic Unversity of Graben, Butembo, COD.
Bienvenu LebwazeAnatomical Pathology, University of Kinshasa, Kinshasa, COD.
Raphael ChirimwamiAnatomical Pathology, University of Kinshasa, Kinshasa, COD.
Dieudonné SandukuSurgical Gastroenterology, University of Kinshasa, Kinshasa, COD.
Antoine BeltchikaNeurosurgery, University of Kinshasa, Kinshasa, COD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumors of the craniovertebral junction (CVJ) are rare and present a major surgical challenge due to the anatomical complexity of the region. We report three cases that were admitted and operated on in our department. All three patients presented with motor deficits and bladder-sphincter dysfunction. In the first case, MRI revealed a grossly ovoid tumor measuring 30 x 28 mm, located anterolaterally to the right of the cervical spinal cord at the level of the C2 vertebral body, extending anteriorly beyond the arch of C1. The second patient's contrast-enhanced MRI showed an intradural extramedullary lesion measuring 31 x 27 mm at the C2-C3 level. In the third case, imaging demonstrated spinal cord compression at the C1-C2 level due to a mass measuring 35 x 26 mm in the extradural and extramedullary space, with spontaneous signal located anterior to the dural sac. All patients underwent posterior decompression. Tumor excision was performed under a neurosurgical microscope following C2 laminectomy and partial resection of the posterior arch of C1 in all three cases. Histopathological examination of the resected specimens confirmed the diagnosis of schwannomas. Postoperative outcomes were uneventful, and all patients showed improvement following physiotherapy sessions. This case series highlights the surgical complexity of the posterior approach to CVJ tumors, particularly giant schwannomas, and demonstrates the favorable postoperative course following complete resection.

Indexed as

cranio-cervical junction tumorextradural tumorschwannomaslow spinal cord compressionspinal surgeryspinal tumors

Identifiers

PMID40964467
PMCPMC12439001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.