Evidence map›Paper›PMID 40964389›Full record

ArticlebioRxiv : the preprint server for biology2025

A bacterial PrimPol-reverse transcriptase hybrid protein has a proofreading exonuclease activity that can be transferred to other reverse transcriptases.

Seungjin Kim, Hengyi Xu, Georg Mohr, Jun Yao, Y Jessie Zhang, Guzhen Cui, Alan M Lambowitz

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seungjin KimDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0009-0001-7168-3385
Hengyi XuDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0001-9809-4882
Georg MohrDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-6411-0685
Jun YaoDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-1232-1587
Y Jessie ZhangDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-9360-5388
Guzhen CuiDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-6520-1052
Alan M LambowitzDepartment of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0001-6036-2423

Funding

Group II Intron and Related Reverse TranscriptasesR35GM136216 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ALAN M. LAMBOWITZ · 2020 to 2026
$6.0M
NIGMS NIH HHS R35 GM136216
6 · The paper itself

Abstract

Gene disruption analysis revealed that an

Indexed as

biotechnologyDNA sequencingDRT7genome engineeringnon-LTR-retroelementsPrimase-PolymeraseretrovirusesRNA-dependent RNA polymerasesRNA sequencingTGIRT-seqUG10

Identifiers

PMID40964389
PMCPMC12439943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.