ArticlebioRxiv : the preprint server for biology2025
Lysosomal RNA profiling reveals targeting of specific types of RNAs for degradation.
G Jordan Ray, Eleonora Nardini, Heather R Keys, Daniel H Lin, David M Sabatini, David P Bartel
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
6 authors.
G Jordan RayDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.ORCID 0000-0002-1245-8428 Eleonora NardiniWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Heather R KeysWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
Daniel H LinWhitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
David M SabatiniInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic.
David P BartelDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Funding
PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8MRegulation of the mTOR Pathway By NutrientsR01CA103866 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2004 to 2021
$7.0MCell Growth Signaling in Cancer DevelopmentR01CA129105 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2008 to 2021
$5.9MTRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALINGR01AI047389 · NIAID · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2000 to 2021
$4.9MUnderstanding the Starvation Induced Selective Autophagy of Specific mRNAs and lncRNAsF31GM129905 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI RAY, GRAHAM JORDAN · 2018 to 2019
$90kNCI NIH HHS R01 CA103866NCI NIH HHS R01 CA129105NIAID NIH HHS R01 AI047389NIGMS NIH HHS F31 GM129905NIGMS NIH HHS T32 GM007287
6 · The paper itselfAbstract
Autophagy targets a wide variety of substrates for degradation within lysosomes
Identifiers
PMID40964324
PMCPMC12439944
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