Evidence map›Paper›PMID 40964242›Full record

ArticlebioRxiv : the preprint server for biology2025

Chondrolectin regulates the sublaminar localization and regenerative function of muscle satellite cells in mice.

Lijie Gu, Kun Ho Kim, Xiyue Chen, Stephanie N Oprescu, Yufen Li, Junxiao Ren, Shihuan Kuang, Feng Yue

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lijie GuDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Kun Ho KimDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Xiyue ChenDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Stephanie N OprescuDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Yufen LiDepartment of Animal Sciences, University of Florida, Gainesville, FL 32611, USA.
Junxiao RenDepartment of Animal Sciences, University of Florida, Gainesville, FL 32611, USA.
Shihuan KuangDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0001-9180-3180
Feng YueDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-5856-3506

Funding

Immunomyoblasts in muscle regenerationR01AR078695 · NIAMS · PURDUE UNIVERSITY · PI KUANG, SHIHUAN · 2021 to 2025
$2.2M
Metabolic regulation of muscle satellite cell homeostasisR01DK132819 · NIDDK · PURDUE UNIVERSITY · PI Shihuan Kuang · 2023 to 2026
$2.0M
NIAMS NIH HHS R01 AR078695NIDDK NIH HHS R01 DK132819
6 · The paper itself

Abstract

Skeletal muscle satellite cells (SCs) reside between the myofiber sarcolemma and basal lamina, where extracellular matrix (ECM) interactions are essential for their maintenance and regenerative function. Here, we identify chondrolectin (CHODL), a type I transmembrane protein with a C-type lectin domain, as a critical regulator of SC biology. Single-cell RNA-seq analysis reveals that

Indexed as

CHODLExtracellular matrixMuscle regenerationSatellite cellStem cell niche

Identifiers

PMID40964242
PMCPMC12440028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.