Insomnia Improved by Intravenous Mesenchymal Stem Cell Transplant: A Case Report.

Abstract readCase Reports

In one paragraph

Article in Sleep science (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Takahiro Honda PaziliRegenerative Medicine, Department of Cell Therapy, Japan Tokyo Stem Cell Transplant Research Institute, Cyuou-ku, Tokyo, Japan.ORCID 0000-0001-9427-7913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While several therapeutic options for insomnia are currently available, they often require long-term use and come with certain disadvantages. Given insomnia's significant impact on health overall, more effective treatments are warranted. Here, we report two patients with moderate to severe insomnia whose symptoms significantly improved following the intravenous administration of

Indexed as

cell transplantationinsomniainterleukin-4mesenchymal stem cells

Identifiers

PMID40964225

DOI10.1055/s-0045-1809993

PMCPMC12440579

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.