ReviewFrontiers in cellular neuroscience2025
Research progress of kinesin family in neurological diseases.
Review in Frontiers in cellular neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Identification of a metastasis-associated prognostic gene signature in osteosarcoma through integrated bioinformatics and functional analysis.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Clinical Utility of Trio Exome Sequencing in Rwandan Children With Autism Spectrum Disorder.Molecular genetics & genomic medicine · 2026Article
- The deficiency of KIF2C leads to abnormal distribution of cortical neurons and behavioral deficits in mice.iScience · 2026Article
- Traffic Jams in the Brain: How Kinesin Dysfunction Shapes Neurodevelopmental Disorders.Current issues in molecular biology · 2026Review
- Correlation Analysis ofGenes · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kinesin superfamily proteins (KIFs) constitute a pivotal class of molecular motors that facilitate the intracellular transport of cellular "cargo." Their principal functions encompass the participation of the transport of cellular substances along microtubules, as well as the engagement in the formation of the mitotic spindle and the segregation of chromosomes during cellular mitosis. Dysregulation of KIFs expression can precipitate anomalies in intracellular material transport, mitotic abnormalities, aberrant cell proliferation and migration, and genomic instability within cells. Moreover, members of the KIFs are implicated in the proliferation of neural progenitor cells and the migration of neurons, which are critical processes in the development of the central nervous system. To date, an extensive body of research has substantiated the close correlation between mutations or aberrant expression of KIFs and the onset of neurological disorders, including neurotumors, neurodegenerative disease, and psychiatric illnesses. This review will synthesize recent research elucidating the nexus between KIFs and neurodevelopment, as well as their association with neurological diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.