Evidence map›Paper›PMID 40964084›Full record

ArticleArXiv2025

What do the fundamental constants of physics tell us about life?

Pankaj Mehta, Jané Kondev

Abstract readPreprint
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pankaj MehtaDepartment of Physics and Faculty for Computing and Data Science, Boston University, Boston MA & 02215, USA.
Jané KondevMartin A. Fisher School of Physics, Brandeis University, Waltham MA & 02453, USA.

Funding

MODELING EMERGENT BEHAVIORS IN SYSTEMS BIOLOGY: A BIOLOGICAL PHYSICS APPROACHR35GM119461 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Pankaj Mehta · 2016 to 2026
$3.6M
NIGMS NIH HHS R35 GM119461
6 · The paper itself

Abstract

In the 1970s, the renowned physicist Victor Weisskopf famously developed a research program to qualitatively explain properties of matter in terms of the fundamental constants of physics. But there was one type of matter prominently missing from Weisskopf's analysis: life. Here, we develop Weisskopf-style arguments demonstrating how the fundamental constants of physics can be used to understand the properties of living systems. By combining biophysical arguments and dimensional analysis, we show that vital properties of chemical self-replicators, such as growth yield, minimum doubling time, and minimum power consumption in dormancy, can be quantitatively estimated using fundamental physical constants. The calculations highlight how the laws of physics constrain chemistry-based life on Earth, and if it exists, elsewhere in our universe.

Identifiers

PMID40964084
PMCPMC12440066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.