Evidence map›Paper›PMID 40964054›Full record

ArticleFrontiers in cellular and infection microbiology2025

Pan-cancer analysis reveals intratumoral microbial diversity in multiple cancers by amplicon technology.

Xudong Liu, Yuteng Yao, Aoyi Xiao, Dingyan Cao, Jingheng Zhang, Yanan Shi, Qing Zhong, Zilong He, Wenming Wu

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Intratumoral Microbiome of Metastatic Pancreatic Ductal Adenocarcinoma.International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xudong Liu *Laboratory Animal Research Facility, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Yuteng Yao *School of Life Sciences, Henan University, Kaifeng, Henan, China.
Aoyi Xiao *Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Dingyan CaoDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Jingheng ZhangDepartment of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Yanan ShiBiomedical Engineering Facility of National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qing ZhongBiomedical Engineering Facility of National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zilong HeSchool of Engineering Medicine, Beihang University, Beijing, China.
Wenming WuThe State Key Laboratory for Complex, Severe, and Rare Diseases, Peking Union Medical College Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite numerous studies investigating intratumoral microorganisms and their significant roles in cancer initiation, progression, and treatment efficacy, a systematic understanding of intratumoral microorganisms remains lacking. Herein, we conducted a study using 16S rDNA data on seven types of cancer, comprising a total of 783 samples. It's worth noting that

Indexed as

BacteriaBiodiversityMicrobiotaNeoplasmsDNA, BacterialDNA, RibosomalHumansPhylogenyPrevotellaPseudomonasRNA, Ribosomal, 16SSequence Analysis, DNAStreptococcusDNA, BacterialDNA, RibosomalRNA, Ribosomal, 16S16S rDNAintratumoral microbialpan-cancerprevotellapseudomonasstreptococcus

Identifiers

PMID40964054
PMCPMC12438974

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.