ArticleFrontiers in neurology2025
Efficacy of electroacupuncture on insomnia disorder in older adults: study protocol for a multicentre randomised controlled trial.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Mechanism-Driven Translation of Electroacupuncture for Depression: Bridging the Gap Between Preclinical and Clinical Research.Neuropsychiatric disease and treatment · 2026Review
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Authors and funding
13 authors.
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Abstract
Introduction: Insomnia disorder is highly prevalent among older adults and is associated with significant adverse effects on both physical and psychological health. The use of hypnotic medications in this population is often accompanied by undesirable risks, including drug tolerance, dependence, and impaired daytime functioning. While electroacupuncture has been increasingly employed as a therapeutic modality for insomnia, robust clinical evidence supporting its efficacy and safety remains limited. This multicentre randomised controlled trial is designed to evaluate the therapeutic effectiveness and safety profile of electroacupuncture in the treatment of insomnia disorder in older adults. Methods and analysis: This multi-centre, single-blind, randomised controlled trial will enrol 214 older adults with diagnosed insomnia disorder from five hospitals. Participants will be randomly assigned in a 1:1 ratio to receive either electroacupuncture or sham electroacupuncture. The electroacupuncture group will undergo treatment three times per week for 8 weeks. The sham electroacupuncture group will receive a non-penetrative placebo needle intervention at sham acupoints, with no electrical stimulation delivered despite connection to the electroacupuncture apparatus. The primary outcome will be the change in Pittsburgh Sleep Quality Index score. Secondary outcomes will include the Insomnia Severity Index, actigraphy-derived sleep parameters, sleep diaries, the Hospital Anxiety and Depression Scale, and the Mini-Mental State Examination. All outcomes will be assessed at baseline (week 0), during intervention (weeks 4 and 8), and during follow-up (weeks 12 and 20). Discussion: If the intervention demonstrates efficacy, this study will provide important clinical evidence supporting electroacupuncture as a safe and effective non-pharmacological treatment for insomnia in older adults. The findings may influence clinical practice by expanding therapeutic options and improving sleep quality in this vulnerable population. Clinical trial registration: http://www.chictr.org.cn, identifier ChiCTR2400081782.
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