Evidence map›Paper›PMID 40963854›Full record

ArticleFrontiers in oncology2025

Risk factors for thrombotic events in Philadelphia chromosome-negative myeloproliferative neoplasms: a retrospective analysis of 336 cases.

Lingxiu Zhang, Xiufeng Wang, Man Yang, Youmei Zi, Yuan Zhang, Yan Guo, Guoqing Lv, Sun Wu, Yan Huang

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In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Lingxiu ZhangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Xiufeng WangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Man YangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Youmei ZiDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Yuan ZhangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Yan GuoDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Guoqing LvDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Sun WuDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
Yan HuangDepartment of Hematology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic events are one of the main factors affecting the survival of patients with Philadelphia chromosome-negative (Ph-) myeloproliferative neoplasms (MPNs). Therefore, a comprehensive understanding of the early relevant high-risk factors makes sense for early prevention and reducing mortality in these patients. In this study, we conducted a retrospective analysis of 336 patients with Ph- MPN and summarized the clinical characteristics, incidence of thrombotic events and influencing factors. Thrombotic events occurred in 27.7% (93/336) of patients. Among the thrombotic events, arterial thrombosis occurred in 86 cases (92.5%), the most common thrombotic event was cerebral infarction (69/93, 74.2%). Univariate analysis and logistic regression identified that diagnosis of Polycythemia Vera (PV)/Essential Thrombocythemia (ET), thrombotic events before diagnosis and D-dimer≥1mg/L were the independent risk factors for thrombotic events at initial diagnosis in MPN patients (

Indexed as

clinical characteristicsmyeloproliferative neoplasmsretrospective analysisrisk factorsthrombotic events

Identifiers

PMID40963854
PMCPMC12436128

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