Evidence map›Paper›PMID 40963807›Full record

ArticleFrontiers in neuroscience2025

Assessing the impact of posture on brain volume in healthy subjects with a rotatable cryogen-free 1.5T superconducting MRI.

Shiying Ke, Yulin Wang, Jichang Zhang, Jie Zeng, Shengyang Niu, Jianjun Zheng, Thomas Meersmann, Chengbo Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shiying KeDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, China.
Yulin WangDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, China.
Jichang ZhangDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, China.
Jie ZengDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, China.
Shengyang NiuDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, China.
Jianjun ZhengDepartment of Radiology, Ningbo No. 2 Hospital, Ningbo, China.
Thomas MeersmannSchool of Medicine, Sir Peter Mansfield Imaging Centre, Translational Medical Sciences, University of Nottingham, Nottingham, United Kingdom.
Chengbo WangDepartment of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham Ningbo China, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Magnetic Resonance Imaging (MRI) is crucial for detailed visualization of brain structure and function. However, conventional supine imaging limits the exploration of how posture impacts brain morphology. While recent advancements in upright MRI systems have enabled studies of postural effects on various body systems, investigations into posture's impact on brain anatomy remain limited. Method: This study investigated volumetric differences between upright and supine positions to establish a baseline for future investigations into how posture influenced brain structure. Thirty-one healthy volunteers underwent scans using a rotatable cryogen-free 1.5T MRI scanner in supine and upright postures. The 3D T1-weighted MP-RAGE brain images were segmented into 109 regions, and volume changes across these regions were analyzed. Result: Volumetric analysis across 109 brain regions in both supine and upright postures shows minimal changes, with most regions displaying variations within a ±5% range. The coefficient of variation (COV) indicated that posture-induced volume changes are even smaller than the measurement precision of the method. These findings provide a solid groundwork for future studies on the effects of posture on brain structure. Conclusion: The majority of brain regions exhibited no significant volumetric differences between supine and upright positions, suggesting that brain structure remains consistent and stable across different postures. These findings offer valuable insights for future research on the postural influences on brain morphology.

Indexed as

brain structuresMP-RAGEMRIpostural effectsvolumetric differences

Identifiers

PMID40963807
PMCPMC12436370

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.