Evidence map›Paper›PMID 40963805›Full record

ArticleInternational journal of women's health2025

Impact of Intraoperative Postural Transitions on Internal Carotid Artery Blood Flow During Gynecologic Laparoscopic Surgery.

Xi Tan, Wenyi Sun, Hao Zhou, Li Zhang, Chaoxuan Dong

Abstract read
In one paragraph

Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xi TanDepartment of Anesthesiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, 5106303, People's Republic of China.
Wenyi SunDepartment of Anesthesiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, 5106303, People's Republic of China.
Hao ZhouDepartment of Anesthesiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, 5106303, People's Republic of China.
Li ZhangDepartment of Clinical Medicine, The International School of Jinan University, Jinan University, Guangzhou, Guangdong, 510630, People's Republic of China.
Chaoxuan DongDepartment of Anesthesiology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangdong, 5106303, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Reduced internal carotid artery (ICA) blood flow can cause cerebral hypoperfusion, increasing the risk of intraoperative or postoperative cerebral ischemia. In laparoscopic surgery, postural changes and pneumoperitoneum may further compromise ICA hemodynamics. This study aims to evaluate the effects of intraoperative postural transitions on ICA blood flow in patients undergoing gynecologic laparoscopic surgery. Methods: A single-center, prospective, non-randomized observational study was performed. Measurements of ICA blood flow, heart rate (HR), and mean arterial pressure (MAP) were obtained at eight intraoperative time points: upon arrival to the operating table while awake (T1), post-induction of anesthesia in the supine position (T2), following pneumoperitoneum in the supine position (T3), immediately after placement in the Trendelenburg position (T4), 10 minutes (T5) and 20 minutes (T6) after Trendelenburg positioning, upon return to the supine position (T7), and at the conclusion of surgery (T8). Results: A total of 79 patients were enrolled in this study. A significant reduction in ICA blood flow was observed at T2 compared to T1 (263.8 ± 11.4 vs 323.5 ± 12.0 mL/min, Conclusion: Intraoperative postural transitions during gynecologic laparoscopic surgery are associated with fluctuations in ICA blood flow. The return from the Trendelenburg to the supine position results in a marked decrease in ICA blood flow, HR, and MAP. Clinical Trial Registration: https://www.chictr.org.cn/showproj.html?proj=178094, Identifier: ChiCTR2200065104, Registered October 27, 2022.

Indexed as

gynecologic laparoscopic surgeryinternal carotid artery blood flowintraoperative posture changesTrendelenburg position

Identifiers

PMID40963805
PMCPMC12439691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.