Evidence map›Paper›PMID 40963692›Full record

ArticleFrontiers in transplantation2025

Ischemia-reperfusion injury with a model of porcine whole-blood

Jean-Baptiste Menager, Julia Mercier, Justin Issard, Maria-Rosa Ghigna, Jeanne Tran Van Nhieu, Benoit Decante, Julien Guihaire, Elie Fadel, Fabrice Antigny, Olaf Mercier

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Article in Frontiers in transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jean-Baptiste MenagerINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Julia MercierINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Justin IssardINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Maria-Rosa GhignaINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Jeanne Tran Van NhieuIMRB INSERM U955, Paris-Est Créteil University, Créteil, France.
Benoit DecanteINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Julien GuihaireINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Elie FadelINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Fabrice AntignyINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Olaf MercierINSERM UMR_S 999, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Marie Lannelongue Hospital, Le Plessis-Robinson, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Our objective was to model Ischemia-Reperfusion (IR) injuries by Methods: Lungs and whole blood were collected from 12 pigs and submitted to cold ischemia time (CIT) of 1 or 18 h. The lungs were then ventilated and perfused for 6 h at 37°C using donor whole blood. Pulmonary pressure was 20 mmHg. Results: Compared to the short CIT group, the long CIT group had a lower maximum perfusion flow rate (mean difference in % cardiac output, -39%; 95% CI, -66 to -12; Conclusion: After 18 h of CIT,

Indexed as

animal modelischemia-reperfusionlung transplantorgan perfusionprimary graft dysfunction

Identifiers

PMID40963692
PMCPMC12436443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.