ArticleFrontiers in pharmacology2025
Dilatory effects and safety of a polyphenol-rich extract of
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Coumarins in hypertension management: from vascular signaling pathways to clinical perspectives.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Toxicological Evaluation of the Liver and Kidneys of Rats Exposed toJournal of experimental pharmacology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hypertension is a major global public health concern. Many communities in developing countries still rely on medicinal plants as a source of primary healthcare for treatment of hypertension instead of conventional antihypertensive drugs. Aims of the study: This study evaluated the vasorelaxant effect of a phenolic-rich extract from the roots of Methods: Fresh roots of Results: The total polyphenol content ranged from 952 ± 3.40 mg gallic acid equivalent (GAE/100 g) to 97.8 ± 1.20 mg GAE/100 g of dry extract. The methanolic extract induced significant dilatory effects on the endothelium intact and denuded aortic rings, with the maximum percentage relaxation of 98.9% ± 0.714% and 97.29% ± 3.34%, respectively. The median IC Conclusion: This study demonstrated that the polyphenol-rich extract of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.