ArticleFrontiers in medicine2025
Effects of graded exercise rehabilitation on inflammatory factors and T-lymphocyte subsets in patients with acute exacerbation of chronic obstructive pulmonary disease: a randomized controlled trial.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Predictive value of admission levels of IL-6 and PCT combined with the peri-treatment change in NLR (ΔNLR) for hospital length of stay in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).American journal of translational research · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To evaluate the effects of a 2-week graded exercise rehabilitation program on respiratory function, exercise capacity, inflammatory markers, and immune function in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: This is a prospective randomized controlled trial aimed at evaluating the efficacy of the graded exercise rehabilitation therapy based on the GOLD guidelines in patients with AECOPD. We divided the patients into the intervention group and the control group using the random number table method, with 35 patients in each group. The control group received conventional symptomatic treatment and exercise rehabilitation, while the intervention group underwent graded exercise rehabilitation according to the GOLD guidelines, twice a day, each session lasting 30-45 min, for a total duration of 2 weeks. After the treatment, the main indicators included serum inflammatory factors and T lymphocyte subsets. Secondary indicators included exercise endurance (6MWT), disease symptom burden (CAT), dyspnea (mMRC), self-care ability (ADL), and psychological state (HADS). The hospitalization time, duration of non-invasive mechanical ventilation, and the overall incidence of related complications were also evaluated. All evaluations were conducted 2 weeks before and after the rehabilitation treatment. Results: Baseline characteristics were comparable between groups. Post-intervention, both groups showed significant improvements in all measured parameters ( Conclusion: The GOLD-based graded exercise rehabilitation demonstrates superior clinical efficacy compared to conventional rehabilitation for AECOPD patients, showing significant benefits in reducing systemic inflammation, improving immune function, and enhancing physical and psychological outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.