Evidence map›Paper›PMID 40963385›Full record

ArticleDermatology reports2026

Unusual site presentation of dermatitis herpetiformis: line-field confocal optical coherence tomography for effective management.

Luca Bettolini, Stefano Bighetti, Sara Rovaris, Iacopo Ghini, Vincenzo Maione

Abstract read
In one paragraph

Article in Dermatology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luca BettoliniDermatology Department, University of Brescia, ASST Spedali Civili di Brescia.ORCID 0000-0003-4374-802X
Stefano BighettiDermatology Department, University of Brescia, ASST Spedali Civili di Brescia.ORCID 0009-0006-2781-6909
Sara RovarisDermatology Department, University of Brescia, ASST Spedali Civili di Brescia.ORCID 0000-0001-5454-4220
Iacopo GhiniPathology Department, University of Brescia, ASST Spedali Civili di Brescia.
Vincenzo MaioneDermatology Department, University of Brescia, ASST Spedali Civili di Brescia.ORCID 0000-0002-0420-5009

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatitis herpetiformis (DH) is an uncommon autoimmune blistering skin disorder linked to gluten sensitivity. This report describes the line-field confocal optical coherence tomography (LC-OCT) features in a DH case, correlating with histopathological findings. A 60-year-old man exhibited erythematous papules and vesicles on the trunk with itching and burning, alongside alternating bowel issues. LC-OCT revealed subepidermal hypo-reflective areas with hyper-reflective floating cells at the dermal papillae tips. Histopathology showed subepidermal vesiculation and neutrophilic microabscesses, confirmed by granular IgA deposits in the dermal papillae via direct immunofluorescence (DIF). The patient tested positive for anti-tissue transglutaminase antibodies, was referred to a gastroenterologist, and began dapsone treatment, resolving the skin lesions. LC-OCT findings were consistent with histopathology, supporting its utility in diagnosing DH. Despite clinical similarities between DH and other blistering disorders, LCOCT offers a non-invasive diagnostic approach, aiding in identifying optimal biopsy sites and expediting treatment. Further studies are warranted to validate LC-OCT's potential.

Indexed as

dermatitis herpetiformisLC-OCTnon-invasive diagnosis

Identifiers

PMID40963385
PMCPMC13324603

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.