Evidence map›Paper›PMID 40963231›Full record

ArticleArchives of environmental & occupational health2025

Tailored light intervention for sleep and cognition in World Trade Center (WTC) cohort.

Ola A Alsalman, Weixin Li, Rafael E de la Hoz, Mariana G Figueiro

Abstract read
In one paragraph

Article in Archives of environmental & occupational health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Home-Based Tailored Light Therapy for Sleep, Mood, and Cognitive Outcomes in Mild Cognitive Impairment: A Randomized Trial.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ola A AlsalmanLight and Health Research Center, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-9317-3557
Weixin LiLight and Health Research Center, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-6900-6361
Rafael E de la HozIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-8949-9279
Mariana G FigueiroLight and Health Research Center, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-7773-9239

Funding

The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Manish Arora · 2014 to 2026
$21.3M
Methodology Issues in a Tailored Light Treatment for Persons with DementiaR01AG034157 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI FIGUEIRO, MARIANA GROSS · 2010 to 2024
$7.9M
The long-term impact of light intervention on sleep physiology and cognition in mild cognitive impairmentR01AG062288 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI FIGUEIRO, MARIANA GROSS, MEDNICK, SARA CAROLE · 2019 to 2023
$3.9M
NIA NIH HHS R01 AG034157NIA NIH HHS R01 AG062288NIEHS NIH HHS P30 ES023515
6 · The paper itself

Abstract

World Trade Center rescue and recovery workers and volunteers (WTC RRWV) are vulnerable to circadian rhythm disruption due to stress and environmental exposures during the 9/11 operation, with high rates of cognitive impairment and poor sleep quality. This exploratory pilot study assessed the feasibility and preliminary effect of a 12-week light-based intervention targeting sleep and cognition. Twenty-three WTC RRWV aged ≥50 years with mild cognitive impairment and sleep disturbances completed the intervention. Sleep, cognition, and circadian-effective light exposures were measured pre-and post-intervention using actigraphy, Pittsburgh Sleep Quality Index, cognitive tasks (go/no-go, digit span, Stroop), and a Daysimeter. Results showed significant improvements in sleep quality and cognitive performance. Greater circadian-effective light exposure was positively associated with improved cognitive accuracy. These preliminary observations suggest that light-based interventions may enhance sleep and cognitive function in at-risk populations.

Indexed as

CognitionCognitive DysfunctionEmergency RespondersPhototherapySeptember 11 Terrorist AttacksSleepSleep Wake DisordersActigraphyAgedCohort StudiesFemaleHumansMaleMiddle AgedNew York CityPilot ProjectsCognitionsleeptailored light interventionWorld Trade Center

Identifiers

PMID40963231
PMCPMC13288221

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.