Evidence map›Paper›PMID 40963204›Full record

ArticleTherapeutic advances in respiratory disease

Nocturnal hypoxemia in COPD: the amplifying effect of comorbid OSA and PLMS on oxygen desaturation.

Viraj Jain, Harshill Modi, Moon Park, Anil Ghimire, Lourdes M DelRosso

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Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Viraj JainLoyola Marymount University, Los Angeles, CA, USA.
Harshill ModiUniversity of California, San Francisco, Fresno, CA, USA.
Moon ParkUniversity of California, San Francisco, Fresno, CA, USA.
Anil GhimireUniversity of California, San Francisco, Fresno, CA, USA.
Lourdes M DelRossoUniversity of California, San Francisco, Fresno, CA, USA.ORCID 0000-0003-3349-8426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD), obstructive sleep apnea (OSA), and periodic limb movements of sleep (PLMS) frequently co-occur and may exacerbate nocturnal hypoxemia. Still, their combined effects are not well defined.

objectivesTo examine the independent and interactive effects of COPD, OSA, and PLMS on nocturnal oxygen desaturation.

designCross-sectional analysis of a sleep study cohort.

methodsWe analyzed 711 participants (mean age 57.2 ± 17.9 years; 44.4% male), including 48 with COPD. Time with oxygen saturation ⩽88% (ST) and mean SpO

resultsParticipants with COPD had lower mean SpO

conclusionCOPD and OSA independently worsen nocturnal hypoxemia, while the coexistence of COPD, OSA, and PLMS confers the greatest desaturation burden, underscoring the importance of evaluating overlapping conditions in clinical assessment.

Indexed as

HypoxiaOxygenOxygen SaturationPulmonary Disease, Chronic ObstructiveSleep Apnea, ObstructiveAdultAgedBiomarkersComorbidityCross-Sectional StudiesFemaleHumansMaleMiddle AgedPolysomnographyRisk FactorsBiomarkersOxygenchronic obstructivehypoxiaobstructiveperiodic limb movement disorderpulmonary diseasesleep apnea

Identifiers

PMID40963204
PMCPMC12444068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.