Evidence map›Paper›PMID 40963116›Full record

ArticleBMC oral health2025

Is there a link between diet and painful temporomandibular disorders? A cross-sectional study.

Camila Cury Marques, Pedro Miguel Teixeira Carvas Cebola, Idoya Orradre Burusco, Maria García González, Miguel de Pedro, Nikolaos Christidis, Malin Ernberg, Giancarlo De la Torre Canales

Erratum issuedAbstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Camila Cury MarquesEgas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.
Pedro Miguel Teixeira Carvas CebolaEgas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal.
Idoya Orradre BuruscoOrofacial Pain, Oral Pathology and Dental Sleep Medicine Research Group, Department of Postgraduate Clinical Dentistry, Faculty of Biomedical Sciences, European University of Madrid, Madrid, Spain.
Maria García GonzálezOrofacial Pain, Oral Pathology and Dental Sleep Medicine Research Group, Department of Postgraduate Clinical Dentistry, Faculty of Biomedical Sciences, European University of Madrid, Madrid, Spain.
Miguel de PedroOrofacial Pain, Oral Pathology and Dental Sleep Medicine Research Group, Department of Postgraduate Clinical Dentistry, Faculty of Biomedical Sciences, European University of Madrid, Madrid, Spain.
Nikolaos ChristidisDivision of Oral Rehabilitation, Department of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Malin ErnbergDivision of Oral Rehabilitation, Department of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.
Giancarlo De la Torre CanalesEgas Moniz Center for Interdisciplinary Research (CiiEM), Egas Moniz School of Health and Science, Almada, Portugal. Giancarlo.de.la.torre.canales@ki.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNutrition and diet have emerged as potentially modifiable factors in the management of chronic pain, however, there is still limited evidence regarding the direct relationship between diet, nutrition, and Temporomandibular disorders (TMD). The aim of this cross-sectional study was to explore the relationship between dietary patterns and painful TMD, with a particular focus on dietary inflammatory potential, adherence to the Mediterranean diet, and psychosocial predictors.

methodsNinety-two participants (45 TMD patients and 47 controls) aged 20–50 were recruited in Portugal and Spain. TMD diagnosis was based on the Diagnostic Criteria for TMD (DC/TMD). Psychosocial status was assessed using PHQ-9 (depression), PHQ-15 (somatic symptoms), and the Oral Behavior Checklist (OBC). Dietary data were collected through a 24-hour recall and assessed using the Healthy Eating Index (HEI), Dietary Inflammatory Index (DII), and Mediterranean Diet Adherence Screener (MEDAS). Pressure pain thresholds (PPT) were recorded at the TMJ and masticatory muscles. Data was analyzed using independent t-tests, Mann-Whitney U, and OPLS-DA multivariate modeling.

resultsTMD patients showed significantly higher scores for somatic symptoms, depressive symptoms, and maladaptive oral behaviors. While no significant differences were found for DII or MEDAS scores between groups, TMD patients had significantly lower HEI scores and PPTs values in the masseter, temporalis, and TMJ regions. OPLS-DA identified oral behaviors, somatic symptoms, and lower HEI as the strongest predictors distinguishing TMD patients from controls.

conclusionsPainful TMD is associated with higher psychosocial distress and poorer dietary quality. These findings underscore the need to include dietary assessment in the clinical evaluation and management of TMD.

Indexed as

DietTemporomandibular Joint DisordersAdultCross-Sectional StudiesDepressionDiet, MediterraneanFemaleHumansMaleMiddle AgedPortugalSpainYoung AdultDietNutritionTemporomandibular disorders

Identifiers

PMID40963116
PMCPMC12442269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.