Evidence map›Paper›PMID 40963033›Full record

Trial reportClinical and experimental nephrology2026

Effects of home-based exercise on physical function and health-related quality of life in older patients with pre-dialysis chronic kidney disease: a single-center randomized controlled trial.

Aki Tabata, Hiroki Yabe, Takehide Katogi, Yuya Mitake, Shunta Oono, Tomoya Yamaguchi, Takayuki Fujii

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical and experimental nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aki TabataDepartment of Rehabilitation, Seirei Sakura Citizen Hospital, 2-36-2 Ebaradai, Sakura-Shi, Chiba, 285-8765, Japan. tabata4107@gmail.com.ORCID http://orcid.org/0000-0002-4758-4838
Hiroki YabeDepartment of Physical Therapy, School of Rehabilitation Sciences, Seirei Christopher University, 3453 Mikatahara, Chuo-ku, Hamamatsu, Shizuoka, 433-8558, Japan.
Takehide KatogiDepartment of Rehabilitation, Seirei Sakura Citizen Hospital, 2-36-2 Ebaradai, Sakura-Shi, Chiba, 285-8765, Japan.
Yuya MitakeDepartment of Rehabilitation, Seirei Sakura Citizen Hospital, 2-36-2 Ebaradai, Sakura-Shi, Chiba, 285-8765, Japan.
Shunta OonoDepartment of Rehabilitation, Seirei Sakura Citizen Hospital, 2-36-2 Ebaradai, Sakura-Shi, Chiba, 285-8765, Japan.
Tomoya YamaguchiDepartment of Rehabilitation, Hamamatsu University Hospital, 1-20-1 Handayama, Chuo-ku, Hamamatsu, Shizuoka, 431-3192, Japan.
Takayuki FujiiDepartment of Nephrology, Seirei Sakura Citizen Hospital, 2-36-2 Ebaradai, Sakura-Shi, Chiba, 285-8765, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise therapy is recommended for patients with chronic kidney disease (CKD), but evidence for its effectiveness in older adults with pre-dialysis CKD is limited.

methodsThis single-center randomized controlled trial examined the effects of a six-month home-based exercise program with monthly counseling in 29 patients aged ≥ 65 years with stage 3-5 pre-dialysis CKD. Participants were randomly assigned to an exercise group (n = 15) or control group (n = 14). Primary outcomes were physical function, measured by 6-min walk distance (6MWD), and health-related quality of life (HRQOL), assessed using the Kidney Disease Quality of Life Short Form (KDQOL-SF). Secondary outcomes included depressive symptoms, nutritional status, and renal function.

results6MWD significantly improved in the exercise group, while no significant change was observed in the control group (p < 0.05). The change in 6MWD was significantly greater in the exercise group than in the control group (p < 0.05). In KDQOL-SF, the role-physical score significantly improved in the exercise group and declined in the control group (p < 0.05). No significant changes were observed in secondary outcomes.

conclusionsA six-month home-based exercise program with counseling improved physical function and HRQOL in older patients with pre-dialysis CKD.

Indexed as

Exercise TherapyHome Care ServicesQuality of LifeRenal Insufficiency, ChronicAgedAged, 80 and overCounselingFemaleHumansKidneyMaleNutritional StatusTreatment OutcomeWalk TestChronic kidney diseaseHealth-related quality of lifeHome-based exerciseOlder patientsPre-dialysis

Identifiers

PMID40963033

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.