Evidence map›Paper›PMID 40963029›Full record

ArticleNature2025

Transitions in dynamical regime and neural mode during perceptual decisions.

Thomas Zhihao Luo, Timothy Doyeon Kim, Diksha Gupta, Adrian G Bondy, Charles D Kopec, Verity A Elliott, Brian DePasquale, Carlos D Brody

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Regulation of the decision threshold by the locus coeruleus.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. InputDSA : Demixing then comparing recurrent and externally driven dynamics.... International Conference on Learning Representations · 2026
    Article
  16. Article
  17. Brain-wide coordination of internal signals during decision-making.bioRxiv : the preprint server for biology · 2025
    Article
  18. Article
  19. Learning neural dynamics through instructive signals.bioRxiv : the preprint server for biology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Thomas Zhihao Luo *Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA. luo@utah.edu.ORCID 0000-0002-7774-1697
Timothy Doyeon Kim *Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA. timkimd@uw.edu.ORCID 0000-0002-0798-9339
Diksha GuptaPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Adrian G BondyPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Charles D KopecPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Verity A ElliottPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Brian DePasqualePrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Carlos D BrodyPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA. brody@princeton.edu.ORCID 0000-0002-4201-561X

Funding

P5: Mechanistic Multi-Region Brain ModelsU19NS132720 · NINDS · PRINCETON UNIVERSITY · PI Carlos D Brody · 2023 to 2026
$21.5M
Cross-brain, multi-region interactions in decision formation and decision commitmentR01MH138935 · NIMH · PRINCETON UNIVERSITY · PI Carlos D Brody · 2024 to 2026
$2.4M
Neural circuit underlying decisions driven by accumulation evidenceR01MH108358 · NIMH · PRINCETON UNIVERSITY · PI BRODY, CARLOS D · 2015 to 2019
$2.0M
Circuit mechanisms of evidence accumulation during decision-makingF32MH115416 · NIMH · PRINCETON UNIVERSITY · PI LUO, ZHIHAO · 2017 to 2021
$230k
NIMH NIH HHS F32 MH115416NIMH NIH HHS R01 MH108358NIMH NIH HHS R01 MH138935NINDS NIH HHS U19 NS132720
6 · The paper itself

Abstract

Perceptual decision-making is thought to be mediated by neuronal networks with attractor dynamics

Indexed as

Decision MakingModels, NeurologicalNeuronsAnimalsDeep LearningFemaleFrontal LobeMaleRatsTime Factors

Identifiers

PMID40963029
PMCPMC12571898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.