Evidence map›Paper›PMID 40963010›Full record

ArticleNature2025

A neuronal architecture underlying autonomic dysreflexia.

Jan Elaine Soriano, Remi Hudelle, Lois Mahe, Matthieu Gautier, Alan Yue Yang Teo, Michael A Skinnider, Achilleas Laskaratos, Steven Ceto, Claudia Kathe, Thomas Hutson and 21 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. In conversation with Grégoire Courtine.Nature neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Jan Elaine Soriano *Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Remi Hudelle *Defitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Lois MaheDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Matthieu GautierDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0003-4910-8576
Alan Yue Yang TeoDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Michael A SkinniderLewis-Sigler Institute of Integrative Genomics and Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-2168-1621
Achilleas LaskaratosDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0002-2456-5781
Steven CetoDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Claudia KatheDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0001-6441-1755
Thomas HutsonWyss Center for Bio and Neuroengineering, Geneva, Switzerland.ORCID 0000-0001-6795-2688
Rebecca CharbonneauDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Fady GirgisDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Steve CashaDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Julien RimokDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Marcus TsoDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-9094-1485
Kelly Larkin-KaiserDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0001-6205-0212
Nicolas HankovDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Aasta GandhiDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0002-6206-6860
Suje AmirDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Xiaoyang KangInstitute of Science and Technology Brain-inspired Intelligence, Fudan University, Shanghai, China.ORCID 0000-0003-4372-9531
Yashwanth VyzaNeuroX Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
Eduardo Martin-MoraudDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0002-6148-7065
Stephanie LacourNeuroX Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.ORCID 0000-0001-9075-4022
Robin DemesmaekerDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.
Leonie AsbothDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0003-2414-9574
Quentin BarraudDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0003-0894-1959
Mark A AndersonDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0003-1855-6106
Jocelyne BlochDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland.ORCID 0000-0002-6405-1590
Jordan W SquairDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland. jordan.squair@epfl.ch.ORCID 0000-0003-0551-859X
Aaron A PhillipsDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. aaron.phillips@ucalgary.ca.ORCID 0000-0002-7845-1464
Gregoire CourtineDefitech Center for Interventional Neurotherapies (.NeuroRestore), CHUV/UNIL/EPFL, Lausanne, Switzerland. gregoire.courtine@epfl.ch.ORCID 0000-0002-5744-4142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autonomic dysreflexia is a life-threatening medical condition characterized by episodes of uncontrolled hypertension that occur in response to sensory stimuli after spinal cord injury (SCI)

Indexed as

Autonomic DysreflexiaNeuronsAnimalsBlood PressureElectric StimulationFemaleHumansMaleMiceMice, Inbred C57BLRatsRats, Sprague-DawleySpinal CordSpinal Cord Injuries

Identifiers

PMID40963010
PMCPMC12571909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.