SynthesisLasers in medical science2025
The use of laser monotherapy in the treatment of keloids and hypertrophic scars: A look at the carbon dioxide laser. A systematic review and meta-analysis.
Synthesis in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Laser treatment of acne scars: a bibliometric analysis and descriptive summary of clinical evidence directions over the past 20 years.Frontiers in medicine · 2026Pooled it
- An Overview of the Mechanisms of Fractional COLasers in medical science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate the effectiveness of fractional CO2 laser monotherapy in treating HS and keloids compared to other laser treatments. A systematic review and meta-analysis were conducted by searching Medline, PubMed, and Cochrane databases for studies comparing fractional CO2 laser therapy to other laser treatments for hypertrophic scars and keloids. Data were analyzed using IBM SPSS Statistics, assessing Vancouver Scar Scale scores, percent improvement in scar characteristics, and patient satisfaction. The search yielded 8,656 articles, with seven studies meeting the inclusion criteria. Analysis included 404 patients with 506 scars. The meta-analysis showed that CO2 laser treatment resulted in significantly better mean VSS scores and percent improvement compared to other lasers. However, there were no significant differences in color, pliability, height, or vascularity improvements and patient satisfaction rates. Fractional CO2 laser therapy is effective in improving the appearance of HS and keloids, with superior outcomes in VSS scores compared to other lasers. Further studies are needed to confirm these findings and to explore combination therapies.
Indexed as
Identifiers
40962972What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.